Patent US4872873A successfully refreshed from Google Patents.
US4872873A
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Controlled release bolus device
Assignee: Alza Corp
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Filing: 1987-12-14
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Granted: 1989-10-10
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Expires: 2007-12-14
Abstract
Abstract This invention relates to an improved controlled release bolus device wherein the improvement comprises attaching at the orifice a screen or insert which prevents blockage of the orifice by exogeneous materials, but does not vary the flow of medicament from the device.
Inventors
- 👤 Joel R. Zingerman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 21:34
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0068
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
170 words
An improved controlled release bolus comprising a semipermeable membrane defining a compartment, the compartment being divided into first and second portions by a moveable interface, the first compartment portion containing a swellable agent, the second compartment portion containing a medicament to be dispensed, a densifier within the second compartment adjacent said membrane and a passageway through the membrane and densifier connecting said second compartment portion with the exterior of the bolus, having a central axis and a diameter such that when the bolus is in contact with water, the semipermeable membrane allow water to pass therethrough which is imbibed by the swellable agent which forces the interface to move the medicament to be dispensed through the passageway, wherein the improvement comprises an insert of rigid film having a central axis which is placed coaxially within the passageway, said inset comprising from 2 to 6 arm members connected together at and extending radially form said central axis of said insert a distance of approximately one-half of the diameter of the passageway.
Claim 2
Dependent Claim
170 words
An improved controlled release bolus comprising a semipermeable membrane defining a compartment, the compartment being divided into first and second portions by a moveable interface, the first compartment portion containing a swellable agent, the second compartment portion containing a medicament to be dispensed, a densifier within the second compartment adjacent said membrane and a passageway through the membrane and densifier connecting said second compartment portion with the exterior of the bolus, having a central axis and a diameter such that when the bolus is in contact with water, the semipermeable membrane allow water to pass therethrough which is imbibed by the swellable agent which forces the interface to move the medicament to be dispensed through the passageway, wherein the improvement comprises an insert of rigid film having a central axis which is placed coaxially within the passageway, said inset comprising from 2 to 6 arm members connected together at and extending radially form said central axis of said insert a distance of approximately one-half of the diameter of the passageway.
Claim 3
Dependent Claim
17 words
The device of claim 1 wherein the rigid film insert extends substantially the length of the passageway.
Claim 4
Dependent Claim
19 words
The device of claim 2, wherein the rigid film insert extends at least half the length of the passageway.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-10-09 | 1993-04-10 | 1993-10-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-10-09 | 1997-04-10 | 1997-10-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-10-09 | 2001-04-10 | 2001-10-10 | $7700.00 | Window Closed / Lapsed |