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US4877586A Expired / Lapsed US ⏱️ 0.0 years remaining

Sliding test device for assays

Assignee: Clinical Diagnostic Systems Inc
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Filing: 1988-07-27
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Granted: 1989-10-31
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Expires: 2008-07-27
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Abstract

Abstract An improved test device, useful in conducting reactions, which comprises (a) a well lconfigured to confine temporarily a liquid patient sample admixed with at least one reagent, such as an immunoreagent, to conduct such a reaction, (b) a filter at the bottom of the well with pores effective to pass free, unreacted reagent but not reacted or complexed reagent, and (c) an absorbent material underneath the filter effective to draw off liquid in the well after the reaction. The device further includes (d) a non-absorbent pad underneath the filter, adjacent to the absorbent material, and (e) means for moving the filter and the absorbent material relative to each other, and the filter and the pad relative to each other, between two positions, one in which the filter contacts the non-absorbent pad and the other in which the filter contacts the absorbent material.

Inventors

  • 👤 Mark J. Devaney, Jr.
  • 👤 Edward H. Wannenwetsch

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 13:08
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01D; B01D61/00; B01D61/14; B01D61/18; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/5302

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 146 words
In a test device useful for conducting a reaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one reagent, to provide said reaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted reagent but not complexed or reacted reagent, and (c) an absorbent material underneath said filter effective to draw off liquid in said well after said reaction, the improvement wherein said device further includes (d) a non-absorbent pad underneath said filter, adjacent to said absorbent material, and (e) means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, one in which said filter contacts said non-absorbent pad and the other in which filter contacts said absorbent material.
Claim 2
Dependent Claim 146 words
In a test device useful for conducting a reaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one reagent, to provide said reaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted reagent but not complexed or reacted reagent, and (c) an absorbent material underneath said filter effective to draw off liquid in said well after said reaction, the improvement wherein said device further includes (d) a non-absorbent pad underneath said filter, adjacent to said absorbent material, and (e) means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, one in which said filter contacts said non-absorbent pad and the other in which filter contacts said absorbent material.
Claim 3
Dependent Claim 30 words
A device as defined in claim 1, wherein said pad and said absorbent material are stationary within said device, and said filter is mounted for movement between said two positions.
Claim 4
Dependent Claim 21 words
A device as defined in claim 2, wherein said moving means comprise means for sliding said filter between said two positions.
Claim 5
Dependent Claim 41 words
A device as defined in claim 3, wherein said pad comprises a rigid hydrophobic plastic material, said device further including means for biasing said filter against said rigid material to temporarily seal said filter from liquid flow occurring through the filter.
Claim 6
Dependent Claim 45 words
A device as defined in claim 4, wherein said pad rests on a first portion of said absorbent material and exposes a second portion of said absorbent material to contact with said filter, whereby said portion of said absorbent material functions as said biasing means.
Claim 7
Dependent Claim 28 words
A device as defined in claim 4, wherein said non-absorbent pad has a beveled surface that facilitates relative movement of said filter and said pad into contacting relationship.
Claim 8
Dependent Claim 43 words
A device as defined in claim 3, wherein said pad comprises a resilient hydrophobic plastic material, and wherein said filter is assembled against said material to slidably seal said filter thereagainst with a pressure effective to temporarily prevent liquid flow through the filter.
Claim 9
Dependent Claim 16 words
A device as defined in claim 1, wherein said absorbent material and said pad are contiguous.
Claim 10
Dependent Claim 30 words
A device as defined in claim 1, wherein said filter is stationary within said device, and said pad and said absorbent material are mounted for movement between said two positions.
Claim 11
Dependent Claim 159 words
In a test device for an immunoreaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one immunoreagent, to provide said immunoreaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted immunoreagent but not complexed immunoreagent, (c) an absorbent material underneath said filter effective to draw off liquid in said well after said immunoreaction, and (d) means for controlling liquid flow from said filter to said absorbent; the improvement wherein said device further includes a non-absorbent pad underneath said filter, and wherein said liquid-controlling means comprise means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, to provide contact of said filter with either said non-absorbing pad or said absorbent material, so that proper alternating conditions of no flow or flow occur.
Claim 12
Dependent Claim 159 words
In a test device for an immunoreaction, said device comprising (a) a well configured to confine temporarily a liquid sample from a patient admixed with at least one immunoreagent, to provide said immunoreaction, (b) a filter at the bottom of said well with pores effective to pass free, unreacted immunoreagent but not complexed immunoreagent, (c) an absorbent material underneath said filter effective to draw off liquid in said well after said immunoreaction, and (d) means for controlling liquid flow from said filter to said absorbent; the improvement wherein said device further includes a non-absorbent pad underneath said filter, and wherein said liquid-controlling means comprise means for moving both (i) said filter and said absorbent material relative to each other and (ii) said filter and said pad relative to each other, between two positions, to provide contact of said filter with either said non-absorbing pad or said absorbent material, so that proper alternating conditions of no flow or flow occur.
Claim 13
Dependent Claim 41 words
A device as defined in claim 10, wherein said pad comprises a rigid hydrophobic plastic material, said device further including means for biasing said filter against said rigid material to temporarily seal said filter from liquid flow occurring through the filter.
Claim 14
Dependent Claim 18 words
A device as defined in claim 11, wherein said biasing means includes a portion of said absorbent material.
Claim 15
Dependent Claim 30 words
A device as defined in claim 10, wherein said filter is stationary within said device, and said pad and said absorbent material are mounted for movement between said two positions.

References Cited (Backward Citations)

US3888629A Cited
US4246339A Cited
US4734262A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-10-30 1993-05-01 1993-10-31 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-10-30 1997-05-01 1997-10-31 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-10-30 2001-05-01 2001-10-31 $7700.00 Window Closed / Lapsed

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