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Wound dressing containing acrylate or methacrylate hydrogel polymer

Assignee: Edison Polymer Innovation Corp
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Filing: 1988-07-22
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Granted: 1989-12-26
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Expires: 2008-07-22
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Abstract

Abstract Acrylate and methacrylate monoesters and diesters having the following formula (I) ##STR1## wherein R 1 , R 2 , R 3 are as defined in the specification, are disclosed. These monomers are polymerizable into hydrogen polymers which are extremely hydrophilic. These hydrogel polymers are useful in the preparation of wound dressings. These polymers form complexes with polyvalent metal ions such as Ca, Mg, Mn and Cu, and possess macrophage stimulating activity in addition to the useful properties possessed by other acrylate and methacrylate hydrogel polymers.

Inventors

  • 👤 Daniel J. Smith
  • 👤 Sanjay R. Patel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 02:25
CPC Classifications
C; C08; C08F; C08F20/00; C08F20/02; C08F20/10; C08F20/34; C08F20/36; A; A61; A61L; A61L26/00; A61L26/0009; A61L26/0014; A61L26/0061; A61L26/008

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 64 words
A wound dressing containing, as a therapeutically active agent, a hydrogel comprising (a) a cross-linked polymer of a major amount of a compound of the formula (I) ##STR11## wherein R 1 is a divalent hydrocarbon radical containing from 2 to about 6 carbon atoms; R 2 is hydrogen, methyl or ethyl; R 3 is hydrogen or methyl; and Y is ##STR12## and (b) water.
Claim 2
Dependent Claim 64 words
A wound dressing containing, as a therapeutically active agent, a hydrogel comprising (a) a cross-linked polymer of a major amount of a compound of the formula (I) ##STR11## wherein R 1 is a divalent hydrocarbon radical containing from 2 to about 6 carbon atoms; R 2 is hydrogen, methyl or ethyl; R 3 is hydrogen or methyl; and Y is ##STR12## and (b) water.
Claim 3
Dependent Claim 23 words
A wound dressing according to claim 1 wherein said polymer is a polymer of a major amount of Quadrol methacrylate or Quadrol dimethacrylate.
Claim 4
Dependent Claim 11 words
A wound dressing according to claim 1 wherein Y is ##STR13##
Claim 5
Dependent Claim 20 words
A wound dressing according to claim 2 wherein said polymer is a polymer of a major amount of Quadrol monomethacrylate.
Claim 6
Dependent Claim 34 words
A wound dressing according to claim 1 wherein said polymer is a polymer of a major amount of said compound of the formula (I) and a minor amount of one or more hydrophilic comonomers.
Claim 7
Dependent Claim 22 words
A wound dressing according to claim 1 wherein said hydrogel has an equilibrium water content of at least 80 percent by weight.

References Cited (Backward Citations)

US4671267A Cited
US4781921A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-12-25 1993-06-26 1993-12-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-12-25 1997-06-26 1997-12-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-12-25 2001-06-26 2001-12-26 $7700.00 Window Closed / Lapsed

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