US4931458A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Heterocyclic rodenticidal compounds, compositions containing the compounds, and methods of use
Assignee: Hoffmann La Roche Inc
•
Filing: 1988-10-05
•
Granted: 1990-06-05
•
Expires: 2008-10-05
Abstract
Abstract Heterocyclic compounds of the formula ##STR1## wherein X is --CH═CH--; R 1 is the group Ar--R 2 or --CH═CH--C(CH 3 )═CH--R 21 ; Ar is phenyl, pyridyl, furyl or thienyl; R 2 is --CO 2 R 3 , --C(O)R 4 , --CH 2 OR 3 , lower-alkylsulphonyl or formyl; R 21 is --CO 2 R 3 , --C(O)R 4 , --CH 2 OR 3 or formyl; R 3 is hydrogen or lower-alkyl; and R 4 is hydrogen, hydroxy, amino, lower-alkyl amino, di-(lower alkyl)amino or lower alkyl; with at least one ring of the molecule being heterocyclic, as well as salts of such compounds are useful in rodenticidal compositions containing a bait to eliminate rodents.
Inventors
- 👤 Michael Klaus
- 👤 Peter Loeliger
- 👤 Harald Weiser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:12
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/78; C07D213/79; C07D213/80; A; A01; A01N; A01N43/00; A01N43/02; A01N43/04; A01N43/06; A01N43/08; A01N43/10; A01N43/12; A01N43/34; A01N43/40; A01N49/00; C07C; C07C29/00; C07C29/36; C07C29/38; C07C29/40; C07C317/00; C07C35/00; C07C35/02; C07C35/08; C07C49/00; C07C49/385; C07C49/403; C07C57/00; C07C57/26; C07D307/00; C07D307/02; C07D307/34; C07D307/56; C07D307/68; C07D307/77; C07D307/78; C07D307/79; C07D333/00; C07D333/02; C07D333/04; C07D333/26; C07D333/38; C07D333/50; C07D333/52; C07D333/54; C07D333/56; C07D333/60; C07D409/00; C07D409/02; C07D409/06; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/655; C07F9/65515; C07F9/65517; C07F9/6553; C07F9/655345; C07C2601/00; C07C2601/12; C07C2601/14
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
66 words
A compound of the formula ##STR8## wherein R 1 is a group Ar--R 2 ; Ar is pyridyl, furyl or thienyl; R 2 is a group --CO 2 R 3 , --C(O)R 4 , --CH.sub. OR 3 , lower-alkylsulphonyl or formyl; R 3 is hydrogen or lower alkyl and R 4 is hydrogen, hydroxy, amino, lower-alkylamino, di-(lower-alkyl)amino or lower alkyl; or a salt of the compound.
Claim 2
Dependent Claim
66 words
A compound of the formula ##STR8## wherein R 1 is a group Ar--R 2 ; Ar is pyridyl, furyl or thienyl; R 2 is a group --CO 2 R 3 , --C(O)R 4 , --CH.sub. OR 3 , lower-alkylsulphonyl or formyl; R 3 is hydrogen or lower alkyl and R 4 is hydrogen, hydroxy, amino, lower-alkylamino, di-(lower-alkyl)amino or lower alkyl; or a salt of the compound.
Claim 3
Dependent Claim
21 words
The compound according to claim 1, wherein R 1 is a group Ar--R 2 in which Ar is thienyl or pyridyl.
Claim 4
Dependent Claim
11 words
The compound according to claim 2, wherein R 2 is lower-alkoxycarbonyl.
Claim 5
Dependent Claim
19 words
The compound according to claim 1, wherein R 1 is a group Ar--R 2 in which Ar is furyl.
Claim 6
Dependent Claim
10 words
the compound according to claim 1, which is ethyl 5-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-2-thiophenecarboxylate.
Claim 7
Dependent Claim
10 words
The compound according to claim 1, which is ethyl 5-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-2-furancarboxylate.
Claim 8
Dependent Claim
10 words
The compound according to claim 1, which is ethyl 6-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]nicotinate.
Claim 9
Dependent Claim
84 words
A rodenticidal composition which comprises inert carrier material and, as the active ingredient, a rodenticidally effective amount of a compound of the formula ##STR9## wherein R 1 is a group Ar--R 2 ; Ar is pyridyl, furyl or thienyl; R 2 is a group --CO 2 R 3 , --C(O)R 4 , --CH 2 OR 3 , lower-alkylsulphonyl or formyl; R 3 is hydrogen or lower-alkyl; and R 4 is hydrogen, hydroxy, amino, lower-alkylamino, di-(lower-alkyl)amino or lower alkyl; or a salt of the compound.
Claim 10
Dependent Claim
84 words
A rodenticidal composition which comprises inert carrier material and, as the active ingredient, a rodenticidally effective amount of a compound of the formula ##STR9## wherein R 1 is a group Ar--R 2 ; Ar is pyridyl, furyl or thienyl; R 2 is a group --CO 2 R 3 , --C(O)R 4 , --CH 2 OR 3 , lower-alkylsulphonyl or formyl; R 3 is hydrogen or lower-alkyl; and R 4 is hydrogen, hydroxy, amino, lower-alkylamino, di-(lower-alkyl)amino or lower alkyl; or a salt of the compound.
Claim 11
Dependent Claim
21 words
The composition according to claim 8, wherein R 1 is a group Ar--R 2 in which Ar is thienyl or pyridyl.
Claim 12
Dependent Claim
19 words
The composition according to claim 8, wherein R 1 is a group Ar--R 2 in which Ar is furyl.
Claim 13
Dependent Claim
14 words
The composition according to claims 9 or 10 in which R 2 is lower-alkoxycarbonyl.
Claim 14
Dependent Claim
14 words
The composition according to claim 8, in which the rodenticidal compound is ethyl 5-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-2-thiophenecarboxylate.
Claim 15
Dependent Claim
14 words
The composition according to claim 8, in which the rodenticidal compound is ethyl 5-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-2-furancarboxylate.
Claim 16
Dependent Claim
14 words
The composition according to claim 8, in which the rodenticidal compound is ethyl 6-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]nicotinate.
Claim 17
Independent Claim
90 words
A method for eliminating rodents which comprises using an effective amount of a compound of the formula ##STR10## wherein R 1 is a group Ar--R 2 ; Ar is pyridyl, furyl or thienyl; R 2 is a group --CO 2 R 3 , --C(O)R 4 , --CH 2 OR 3 , lower-alkylsulphonyl or formyl; R 3 is hydrogen or lower-alkyl; and R 4 is hydrogen, hydroxy, amino, lower-alkylamino, di-(lower-alkyl)aminno or lower alkyl; or a salt of the compound, said compound or salt being present in a bait for said rodents.
Claim 18
Independent Claim
90 words
A method for eliminating rodents which comprises using an effective amount of a compound of the formula ##STR10## wherein R 1 is a group Ar--R 2 ; Ar is pyridyl, furyl or thienyl; R 2 is a group --CO 2 R 3 , --C(O)R 4 , --CH 2 OR 3 , lower-alkylsulphonyl or formyl; R 3 is hydrogen or lower-alkyl; and R 4 is hydrogen, hydroxy, amino, lower-alkylamino, di-(lower-alkyl)aminno or lower alkyl; or a salt of the compound, said compound or salt being present in a bait for said rodents.
Claim 19
Dependent Claim
20 words
The method of claim 15, wherein R 1 is a group Ar--R 2 in which Ar is thienyl or pyridyl.
Claim 20
Dependent Claim
18 words
The method of claim 15, wherein R 1 is a group Ar--R 2 in which Ar is furyl.
Claim 21
Independent Claim
13 words
The method of claims 16 or 17 in which R 2 is lower-alkoxycarbonyl.
Claim 22
Dependent Claim
13 words
The method of claim 15, in which the rodenticidal compound is ethyl 5-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-2-thiophenecarboxylate.
Claim 23
Dependent Claim
13 words
The method of claim 15, in which the rodenticidal compound is ethyl 5-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]-2-furancarboxylate.
Claim 24
Dependent Claim
13 words
The method of claim 15, in which the rodenticidal compound is ethyl 6-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)propenyl]nicotinate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-06-04 | 1993-12-04 | 1994-06-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-06-04 | 1997-12-04 | 1998-06-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-06-04 | 2001-12-04 | 2002-06-05 | $7700.00 | Window Closed / Lapsed |