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US4965392A
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Chelating compounds for metal-radionuclide labeled proteins
Assignee: Poniard Pharmaceuticals Inc
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Filing: 1988-03-23
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Granted: 1990-10-23
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Expires: 2008-03-23
Abstract
Abstract Chelated radionuclide compositions are provided for conjugation to polypeptides and carbohydrates. The resulting conjugates may be used in diagnosis and therapy. Chelating compounds are disclosed.
Inventors
- 👤 Alan R. Fritzberg
- 👤 Sudhakar Kasina
- 👤 Tripuraneni N. Rao
- 👤 Jean-Luc Vanderheyden
- 👤 Ananthachari Srinivasan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:56
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/534; A; A61; A61K; A61K51/00; A61K51/02; A61K51/04; A61K51/0474; A61K51/0478; A61K51/08; A61K51/10; A61K51/1045; A61K51/1066; A61K51/1093; C; C07; C07B; C07B59/00; C07B59/004; C07F; C07F13/00; C07F13/005; C07K; C07K5/00; C07K5/04; C07K5/08; C07K5/0819; A61K2121/00; A61K2123/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
13 words
A compound of the formula: ##STR13## wherein COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 2
Dependent Claim
13 words
A compound of the formula: ##STR13## wherein COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 3
Dependent Claim
13 words
A compound of the formula: ##STR14## wherein COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 4
Dependent Claim
13 words
A compound of the formula: ##STR14## wherein COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 5
Dependent Claim
21 words
A compound of the formula: ##STR15## wherein EOE represents an ethoxyethyl sulfur protecting group and COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 6
Dependent Claim
21 words
A compound of the formula: ##STR15## wherein EOE represents an ethoxyethyl sulfur protecting group and COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 7
Dependent Claim
13 words
A compound of the formula: ##STR16## wherein COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 8
Dependent Claim
13 words
A compound of the formula: ##STR16## wherein COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 9
Dependent Claim
20 words
A compound of the formula: ##STR17## wherein Acm represents an acetamidomethyl sulfur protecting and COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 10
Dependent Claim
20 words
A compound of the formula: ##STR17## wherein Acm represents an acetamidomethyl sulfur protecting and COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 11
Dependent Claim
21 words
A compound of the formula: ##STR18## wherein MOM represents a methoxymethyl sulfur protecting group and COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
Claim 12
Dependent Claim
21 words
A compound of the formula: ##STR18## wherein MOM represents a methoxymethyl sulfur protecting group and COOTFP represents a 2,3,5,6-tetrafluorophenyl ester group.
References Cited (Backward Citations)
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 7.5 Years (Year 8) | 1997-10-22 | 1998-04-23 | 1998-10-23 | $3760.00 | Window Closed / Lapsed |
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