Implantable device for the dosed administration of medicaments to the human body

Claim 2

An implantable device (1) for the dosed administration of medicaments to the human body, comprising a first chamber (4) for storing a medicament, said chamber being provided with a refill opening (12') sealed by means of a pierceable septum (12), and connected via an outlet opening (6) to an outlet catheter (8); and a second chamber (5) which is separated by a flexible diaphragm (3) from said first chamber (4) and serves to apply pressure via said diaphragm (3) to said medicament provided in said first chamber (4), characterized in that a porous hollow fiber capillary (15) disposed at the outlet opening of said first chamber (4) is provided as a filter.

Claim 3

An implantable device (1) according to claim 1, characterized in that an outlet reducing means (7) connecting said outlet opening (6) to said outlet catheter (8) is provided, one end of said outlet reducing means (7) being disposed adjacent said outlet opening (6) and connected to an end of said porous hollow-fiber capillary (15).

Claim 4

An implantable device (1) according to claim 1, characterized in that said hollow fiber capillary (15) is guided through the outlet opening (6) into said first chamber (4).

Claim 5

An implantable device (1) according to claim 1, characterized in that said hollow fiber capillary (15) is inserted inside said first chamber (4) into a groove (16) which is disposed above said diaphragm (3).

Claim 6

An implantable device (1) according to claim 1, characterized in that said hollow fiber capillary (15) is disposed in at least one winding in said first chamber (4).

Claim 7

An implantable device (1) according to claim 1, characterized in that said hollow fiber capillary (15) has an inner diameter of about 200 μm.

Claim 8

An implantable device (1) according to claim 6, characterized in that said hollow fiber capillary (15) has an outer diameter of about 280 μm.

Claim 9

An implantable device (1) according to claim 1, characterized in that a conventional dialyzer diaphragm of polysulfone is used as said hollow fiber capillary (15).

Claim 10

An implantable device (1) according to claim 1, characterized in that a diaphragm which is usable for plasma filtration or plasma fractionation and has a higher exclusion capacity is employed as said hollow fiber capillary (15).

Claim 11

An implantable device (1) according to claim 1, characterized in that said hollow fiber capillary (15) is closed on one side.

Claim 12

An implantable device (1) according to claim 2, characterized in that said hollow fiber capillary (15) is adhered to an end of said outlet reducing means (7).

Claim 13

An implantable device (1) according to claim 11, characterized in that polyurethane is used as an adhesive for adhering said hollow fiber capillary to said end of said outlet reducing means (7).

Claim 14

An implantable device (1) for the dosed administration of medicaments to the human body, comprising a first chamber (4) for storing a medicament, said chamber being provided with a refill opening (12') sealed by means of a pierceable septum (12), and connected via an outlet opening (6) to an outlet catheter (8); and a second chamber (5) which is separated by a flexible diaphragm (3) from said first chamber (4) and serves to apply pressure via said diaphragm (3) to said medicament provided in said first chamber (4), characterized in that porous hollow fiber capillary (15) guided through the outlet opening (6) into said first chamber (4) is provided as a filter.

Claim 15

An implantable device (1) for the dosed administration of medicaments to the human body, comprising a first chamber (4) for storing a medicament, said chamber being provided with a refill opening (12') sealed by means of a pierceable septum (12), and connected via an outlet opening (6) to an outlet catheter (8); and a second chamber (5) which is separated by a flexible diaphragm (3) from said first chamber (4) and serves to apply pressure via said diaphragm (3) to said medicament provided in said first chamber (4), characterized in that porous hollow fiber capillary (15) guided through the outlet opening (6) into said first chamber (4) is provided as a filter.

Claim 16

An implantable device (1) according to claim 13, characterized in that an outlet reducing means (7) connecting said outlet opening (6) to said outlet catheter (8) is provided, one end of said outlet reducing means (7) being disposed adjacent said outlet opening (6) and connected to an end of said porous hollow fiber capillary (15).

Claim 17

An implantable device (1) according to claim 13, characterized in that said hollow fiber capillary (15) is inserted inside said first chamber (4) into a groove (16) which is disposed above said diaphragm (3).

Claim 18

An implantable device (1) according to claim 13, characterized in that said hollow fiber capillary (15) is closed on one side.

Claim 19

An implantable device (1) for the dosed administration of medicaments to the human body, comprising a first chamber (4) for storing a medicament, said chamber being provided with a refill opening (12') sealed by means of a pierceable septum (12), and connected via an outlet opening (6) to an outlet catheter (8); and a second chamber (5) which is separated by a flexible diaphragm (3) from said first chamber (4) and serves to apply pressure via said diaphragm (3) to said medicament provided in said first chamber (4), characterized in that a porous hollow fiber capillary (15) disposed at the outlet opening of said first chamber (4) is provided as a filter, wherein said hollow fiber capillary (15) is inserted inside said first chamber (4) into a groove (16) which is disposed above said diaphragm (3).

Claim 20

An implantable device (1) for the dosed administration of medicaments to the human body, comprising a first chamber (4) for storing a medicament, said chamber being provided with a refill opening (12') sealed by means of a pierceable septum (12), and connected via an outlet opening (6) to an outlet catheter (8); and a second chamber (5) which is separated by a flexible diaphragm (3) from said first chamber (4) and serves to apply pressure via said diaphragm (3) to said medicament provided in said first chamber (4), characterized in that a porous hollow fiber capillary (15) disposed at the outlet opening of said first chamber (4) is provided as a filter, wherein said hollow fiber capillary (15) is inserted inside said first chamber (4) into a groove (16) which is disposed above said diaphragm (3).

Claim 21

An implantable device (1) according to claim 17, characterized in that outlet reducing means (7) connecting said outlet opening (6) to said outlet catheter (8) is provided, one end of said outlet reducing means (7) being disposed adjacent said outlet opening (6) and connected to an end of said porous hollow fiber capillary (15).

Claim 22

An implantable device (1) according to claim 17, characterized in that said hollow fiber capillary (15) is guided through the outlet opening (6) into said first chamber (4).

Claim 23

An implantable device (1) according to claim 1, characterized in that said hollow fiber capillary (15) is closed on one side.