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US5147291A Expired / Lapsed US ⏱️ 0.0 years remaining

Sound transmission apparatus for uniformly administering chemical composition through the skin

Assignee: Individual
•
Filing: 1990-06-11
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Granted: 1992-09-15
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Expires: 2010-06-11
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Abstract

Abstract A method utilizing sound and an aqueous sound transmission gel to transmit minor effective amounts of an anti-inflammatory pharmaceutical agent in uniform quantities through all points in a selected area of the intact skin of the body of an individual.

Inventors

  • 👤 A. David Cukier

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 03:19
CPC Classifications
A; A61; A61M; A61M37/00; A61M37/0092; A61K; A61K31/00; A61K31/56; A61K31/57; A61K41/00; A61K41/0047

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 327 words
A method of uniformly introducing an anti-inflammatory drug at selected points in an area of intact skin, said method including the steps of (a) applying a layer of an aqueous high molecular weight semi-solid sound transmission gel to a selected area of intact skin, said gel (i) including a water soluble anti-inflammatory chemical compound in a concentration in the range of 0.1% to 1.0% by weight, (ii) transmitting sound waves at a speed in the range of 1,200 to 1,700 meters per second, (iii) having a density in the range of 1.01 to 1.5 grams per cubic centimeter, (iv) having a viscosity in the range of 120,000 to 200,000 centipoise at an ambient temperature of 76° F., said viscosity of said gel decreasing when said gel is warmed by the skin of an individual, and (v) having a pH in the range of 6.0 to 7.3; (b) placing a sound transmitting head over said selected area of skin, said head including a smooth face contacting said gel intermediate said sound transmitting head and a portion of said selected area of skin; (c) continuously moving for a period of time greater than four minutes said sound transmitting head over said points in said selected area of skin to knead said skin while maintaining contact between said face and said gel; and, (d) directing sound waves from said head through said gel into said skin while said transmitting head is continuously moved over said selected area of skin, said sound waves having a frequency greater than 0.5 megahertz and driving said chemical compound into said skin; completely off of and moving back over each of said points a generally equivalent number of times to insure that a substantially uniform amount of chemical compound enters the skin at each of said points, the introduction of said anti-inflammatory chemical compound into the skin with said sound transmitting head causing the warming of said skin to reduce the viscosity of said gel.
Claim 2
Independent Claim 327 words
A method of uniformly introducing an anti-inflammatory drug at selected points in an area of intact skin, said method including the steps of (a) applying a layer of an aqueous high molecular weight semi-solid sound transmission gel to a selected area of intact skin, said gel (i) including a water soluble anti-inflammatory chemical compound in a concentration in the range of 0.1% to 1.0% by weight, (ii) transmitting sound waves at a speed in the range of 1,200 to 1,700 meters per second, (iii) having a density in the range of 1.01 to 1.5 grams per cubic centimeter, (iv) having a viscosity in the range of 120,000 to 200,000 centipoise at an ambient temperature of 76° F., said viscosity of said gel decreasing when said gel is warmed by the skin of an individual, and (v) having a pH in the range of 6.0 to 7.3; (b) placing a sound transmitting head over said selected area of skin, said head including a smooth face contacting said gel intermediate said sound transmitting head and a portion of said selected area of skin; (c) continuously moving for a period of time greater than four minutes said sound transmitting head over said points in said selected area of skin to knead said skin while maintaining contact between said face and said gel; and, (d) directing sound waves from said head through said gel into said skin while said transmitting head is continuously moved over said selected area of skin, said sound waves having a frequency greater than 0.5 megahertz and driving said chemical compound into said skin; completely off of and moving back over each of said points a generally equivalent number of times to insure that a substantially uniform amount of chemical compound enters the skin at each of said points, the introduction of said anti-inflammatory chemical compound into the skin with said sound transmitting head causing the warming of said skin to reduce the viscosity of said gel.
Claim 3
Dependent Claim 13 words
The method of claim 1 wherein said chemical compound is dexamethasone disodium phosphate.

References Cited (Backward Citations)

US4657543A Cited
US4702732A Cited
US4767402A Cited
US5016615A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-09-15 1996-03-16 1996-09-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-09-15 2000-03-16 2000-09-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-09-15 2004-03-16 2004-09-15 $7700.00 Window Closed / Lapsed

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