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US5387328A
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Bio-sensor using ion sensitive field effect transistor with platinum electrode
Assignee: SENSOR TECHNOLOGY RESEARCH CENTER OF KYUNGPOOK NATIONAL UNIVERSITY
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Filing: 1993-04-15
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Granted: 1995-02-07
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Expires: 2013-04-15
Abstract
Abstract A bio-sensor employs an ion senstive field effect transistor (ISFET) comping a source 1 and a drain 3 formed in a substrate, an ion sensitive gate 2 placed between the source 1 and drain 3, an ion sensitive film 4 formed on the ion sensing gate 2, an immobilized enzyme membrane 5 defined on the ion sensitive film 4 and, a Pt electrode 6 formed on the ion sensitive film 4. The sensor has a Pt eleletrode being capable of sensing all biological substances which generate H 2 O 2 in enzyme reaction, whereby having the high sensitivity and the rapid reaction time.
Inventors
- 👤 Byung-ki Sohn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 20:57
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/005; G; G01; G01N; G01N27/00; G01N27/26; G01N27/28; G01N27/30; G01N27/327; G01N27/3271; G01N27/3272; G01N27/403; G01N27/414; G01N27/4145; A; A61; A61B; A61B2562/00; G01N2291/00; G01N2291/02; G01N2291/025; G01N2291/0255; Y; Y10; Y10S; Y10S435/00; Y10S435/817
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
76 words
A bio-sensor employing an ion-sensitive field effect transistor (ISFET) comprising: a substrate comprising a source and a drain; an ion sensing gate disposed between the source and the drain; an ion-sensitive film formed on the surface of the substrate and the ion sensing gate; a Pt electrode domain formed on the ion-sensitive film surrounding the periphery of the ion sensing gate; and an immobilized enzyme membrane disposed on the ion-sensitive film and the Pt electrode domain.
Claim 2
Dependent Claim
76 words
A bio-sensor employing an ion-sensitive field effect transistor (ISFET) comprising: a substrate comprising a source and a drain; an ion sensing gate disposed between the source and the drain; an ion-sensitive film formed on the surface of the substrate and the ion sensing gate; a Pt electrode domain formed on the ion-sensitive film surrounding the periphery of the ion sensing gate; and an immobilized enzyme membrane disposed on the ion-sensitive film and the Pt electrode domain.
Claim 3
Dependent Claim
68 words
The bio-sensor according to claim 1, wherein said immobilized enzyme membrane is an immobilized glucose oxidase membrane when the bio-sensor is a glucose sensor, a co-immobilized β-galactosidase and glucose oxidase membrane when the bio-sensor is a lactose sensor, a co-immobilized invertase, mutarotase, and glucose oxidase membrane when the bio-sensor is a sucrose sensor, or an immobilized L-amino acid oxidase membrane when the bio-sensor is an L-amino acid sensor.
Claim 4
Dependent Claim
17 words
The bio-sensor according to claim 2, wherein said immobilized enzyme membrane is an immobilized glucose oxidase membrane.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-02-06 | 1998-08-08 | 1999-02-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-02-06 | 2002-08-08 | 2003-02-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-02-06 | 2006-08-08 | 2007-02-07 | $7700.00 | Window Closed / Lapsed |