US5554367A
Expired / Lapsed
US
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Compositions for treatment of glaucoma
Assignee: Alcon Research LLC
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Filing: 1994-11-04
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Granted: 1996-09-10
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Expires: 2014-11-04
Abstract
Abstract Compositions for controlling glaucoma and ocular hypertension are disclosed.
Inventors
- 👤 Yusuf Ali
- 👤 Rajni Jani
- 👤 George R. McCarty
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 04:01
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; A61K31/765; A61K31/78; A61K31/13; A61K31/135; A61K31/137; A61K31/33; A61K31/395; A61K31/41; A61K31/4164; A61K31/4168; A61K31/4178; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K47/585; A61K9/00; A61K9/0012; A61K9/0048; A61P; A61P27/00; A61P27/02; A61P27/06
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
51 words
A topical ophthalmic composition for controlling glaucoma and/or ocular hypertension comprising 0.1 to 1.0 wt./vol. % betaxolol, 0.25 to 10.0 wt./vol. % pilocarpine, 0.05 to 10.0 wt./vol. % poly(styrene-divinyl benzene) sulfonic acid, and 0.01 to 5.0 wt./vol. % polyanionic polymer selected from the group consisting of Carbomer 934P and Carbomer 974P.
Claim 2
Dependent Claim
51 words
A topical ophthalmic composition for controlling glaucoma and/or ocular hypertension comprising 0.1 to 1.0 wt./vol. % betaxolol, 0.25 to 10.0 wt./vol. % pilocarpine, 0.05 to 10.0 wt./vol. % poly(styrene-divinyl benzene) sulfonic acid, and 0.01 to 5.0 wt./vol. % polyanionic polymer selected from the group consisting of Carbomer 934P and Carbomer 974P.
Claim 3
Dependent Claim
12 words
The composition of claim 1 wherein the polyanionic polymer is Carbomer 934P.
Claim 4
Dependent Claim
28 words
The composition of claim 2 wherein the betaxolol concentration is 0.25%, the pilocarpine concentration is 1.75%, the resin concentration is 0.25%, and the Carbomer 934P concentration is 0.40%.
Claim 5
Dependent Claim
12 words
The composition of claim 1 wherein the polyanionic polymer is Carbomer 974P.
Claim 6
Dependent Claim
28 words
The composition of claim 4 wherein the betaxolol concentration is 0.25%, the pilocarpine concentration is 1.75%, the resin concentration is 0.25%, and the Carbomer 974P concentration is 0.40%.
Claim 7
Independent Claim
56 words
A method for controlling intraocular pressure by topically applying to the eye a composition which comprises 0.1 to 1.0 wt./vol. % betatolol, 0.25 to 10.0 wt./vol. % pilocarpine, 0.05 to 10.0 wt./vol. % poly(styrene-divinyl benzene) sulfonic acid, and 0.01 to 5.0 wt./vol. % polyanionic polymer selected from the group consisting of Carbomer 934P and Carbomer 974P.
Claim 8
Independent Claim
56 words
A method for controlling intraocular pressure by topically applying to the eye a composition which comprises 0.1 to 1.0 wt./vol. % betatolol, 0.25 to 10.0 wt./vol. % pilocarpine, 0.05 to 10.0 wt./vol. % poly(styrene-divinyl benzene) sulfonic acid, and 0.01 to 5.0 wt./vol. % polyanionic polymer selected from the group consisting of Carbomer 934P and Carbomer 974P.
Claim 9
Dependent Claim
12 words
The method of claim 6 wherein the polyanionic polymer is Carbomer 934P.
Claim 10
Dependent Claim
28 words
The method of claim 7 wherein the betaxolol concentration is 0.25%, the pilocarpine concentration is 1.75%, the resin concentration is 0.25%, and the Carbomer 934P concentration is 0.40%.
Claim 11
Dependent Claim
12 words
The method of claim 6 wherein the polyanionic polymer is Carbomer 974P.
Claim 12
Dependent Claim
28 words
The method of claim 9 wherein the betaxolol concentration is 0.25%, the pilocarpine concentration is 1.75%, the resin concentration is 0.25%, and the Carbomer 974P concentration is 0.40%.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1999-09-10 | 2000-03-11 | 2000-09-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-09-10 | 2004-03-11 | 2004-09-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-09-10 | 2008-03-11 | 2008-09-10 | $7700.00 | Window Closed / Lapsed |