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Method and means for inhibiting posterior capsule opacification

Assignee: Pfizer Health AB
•
Filing: 1994-04-26
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Granted: 1996-11-19
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Expires: 2014-04-26
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Abstract

Abstract The present invention is directed to the use of taxol or a pharmaceutically and ophthalmologically acceptable derivative thereof for the prevention of secondary cataracts after extracapsular extraction with or without intraocular lens implantation.

Inventors

  • 👤 Per Månsson
  • 👤 Wenche Rolfsen
  • 👤 Kerstin Wickstr om

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 01:42
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61P; A61P27/00; A61P27/02; A61P27/12; A61K9/00; A61K9/0012; A61K9/0048

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 30 words
A method for preventing secondary cataract after extracapsular cataract extraction, comprising administering taxol or a pharmaceutically active and ophthalmologically acceptable derivative thereof to the intraocular area after extracapsular cataract extraction.
Claim 2
Independent Claim 30 words
A method for preventing secondary cataract after extracapsular cataract extraction, comprising administering taxol or a pharmaceutically active and ophthalmologically acceptable derivative thereof to the intraocular area after extracapsular cataract extraction.
Claim 3
Dependent Claim 24 words
A method as defined by claim 1, wherein an intraocular lens is implanted in the intraocular area before, simultaneous with or after said administration.
Claim 4
Dependent Claim 24 words
A method as defined by claim 1, wherein no intraocular lens is implanted in the intraocular area before, simultaneous with or after said administration.
Claim 5
Dependent Claim 24 words
A method as defined by claim 1, wherein the taxol or the derivative thereof is administered in an amount of up to 25 μg.
Claim 6
Dependent Claim 26 words
A method as defined by claim 1, wherein the taxol or the derivative thereof is administered in an amount of from about 0.005 to 5 μg.
Claim 7
Dependent Claim 25 words
A method as defined by claim 1, wherein the taxol or the derivative thereof is administered in an amount of from 0.1 to 5 μg.
Claim 8
Dependent Claim 20 words
A method as defined by claim 1, wherein the taxol or the derivative thereof is administered in a microcrystalline form.
Claim 9
Dependent Claim 21 words
A method as defined by claim 1, wherein the taxol or the derivative thereof is administered in a slow release composition.
Claim 10
Dependent Claim 22 words
A method as defined by claim 1, wherein the taxol or the derivative thereof is administered in an ophthalmologically acceptable viscoelastic medium.
Claim 11
Dependent Claim 18 words
A method as defined by claim 9, wherein the viscoelastic medium comprises an aqueous solution of hyaluronic acid.
Claim 12
Dependent Claim 22 words
A method as defined by claim 9, wherein the visoelastic medium is administered in an amount of from 0.1 to 0.3 ml.
Claim 13
Dependent Claim 43 words
A method as defined by claim 1, wherein the taxol or a pharmaceutically active and opthalmologically acceptable derivative thereof is administered in microcrystalline form in an amount of about 0.005 to 5 μg in approximately 0.1 ml of an aqueous hyaluronic acid solution.

References Cited (Backward Citations)

US5252319A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-11-19 2000-05-20 2000-11-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-11-19 2004-05-20 2004-11-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-11-19 2008-05-20 2008-11-19 $7700.00 Window Closed / Lapsed

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