Blends of absorbable polyoxaamides

Claim 1

An aliphatic polyoxaamides comprising a first divalent repeating unit of formula I: [X--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)--]I and a second repeating unit selected from the group of formulas consisting of: [--Y--R.sub.17 --].sub.T, II [--O--R.sub.5 --C(O)--].sub.B, III ([--O--R.sub.9 --C(O)].sub.P --O--).sub.L G XI and combinations thereof, wherein X and Y are selected from the group consisting of --O-- and --N(R)--, provided that X and Y cannot both be --O--; R, R 1 and R 2 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 3 is selected from the group consisting of an alkylene unit and an oxyalkylene group of the following formula: --[(CH.sub.2).sub.C --O--].sub.D --(CH.sub.2).sub.E -- IV wherein C is an integer in the range of from 2 to about 5, D is an integer in the range of from 0 to about 2,000, and E is an integer in the range of from about 2 to about 5, except when D is zero, in which case E will be an integer in the range of from 2 to 12; R 17 is an alkylene unit containing from 2 to 8 carbon atoms which may have substituted therein an internal ether oxygen, an internal --N(R 18 )-- or an internal --C(O)--N(R 21 )--; T is an integer in the range of from 1 to 2,000; R 18 and R 21 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 5 and R 9 are selected from the group consisting of --C(R 6 )(R 7 )--, --(CH 2 ) 3 --O--, --CH 2 --CH 2 --O--CH 2 --, --CR 8 H--CH 2 --, --(CH 2 ) 4 --, --(CH 2 ) F --O--C(O)-- and --(CH 2 ) K --C(O)--CH 2 --; R 6 and R 7 are independently selected from the group consisting of hydrogen and an alkyl containing from 1 to 8 carbon atoms; R 8 is selected from the group consisting of hydrogen and methyl; F and K are independently selected integer in the range of from 2 to 6; B is an integer in the range of from 1 to n such that the number average molecular weight of formula III is less than about 200,000; P is an integer in the range of from 1 to m such that the number average molecular weight of formula XI is less than about 1,000,000; G represents the residue minus from 1 to L hydrogen atoms from the hydroxyl groups of an alcohol previously containing from 1 to about 200 hydroxyl groups; and L is an integer from about 1 to about 200.

Claim 6

A device made from an aliphatic polyoxaamides comprising a first divalent repeating unit of formula I: [X--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)--]I and a second repeating unit selected from the group of formulas consisting of: [--Y--R.sub.17 --].sub.T, II [--O--R.sub.5 C(O)--].sub.B, III ([--O--R.sub.9 --C(O)].sub.P --O--).sub.L G XI and combinations thereof, wherein X and Y are selected from the group consisting of --O-- and --N(R)--, provided that X and Y cannot both be --O--; R, R 1 and R 2 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 3 is selected from the group consisting of an alkylene unit and an oxyalkylene group of the following formula: --[(CH.sub.2).sub.C --O--].sub.D --(CH.sub.2).sub.E -- IV wherein C is an integer in the range of from 2 to about 5, D is an integer in the range of from 0 to about 2,000, and E is an integer in the range of from about 2 to about 5, except when D is zero, in which case E will be an integer in the range of from 2 to 12; R 17 is an alkylene unit containing from 2 to 8 carbon atoms which may have substituted therein an internal ether oxygen, an internal --N(R 18 )-- or an internal --C(O)--N(R 21 )--; T is an integer in the range of from 1 to 2,000; R 18 and R 21 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 5 and R 9 are selected from the group consisting of --C(R 6 )(R 7 )--, --(CH 2 ) 3 --O--, --CH 2 --CH 2 --O--CH 2 --, --CR 8 H--CH 2 --, --(CH 2 ) 4 --, --(CH 2 ) F --O--C(O)-- and --(CH 2 ) K --C(O)--CH 2 --; R 6 and R 7 are independently selected from the group consisting of hydrogen and an alkyl containing from 1 to 8 carbon atoms; R 8 is selected from the group consisting of hydrogen and methyl; F and K are independently selected integer in the range of from 2 to 6; B is an integer in the range of from 1 to n such that the number average molecular weight of formula III is less than about 200,000; P is an integer in the range of from 1 to m such that the number average molecular weight of formula XI is less than about 1,000,000; G represents the residue minus from 1 to L hydrogen atoms from the hydroxyl groups of an alcohol previously containing from 1 to about 200 hydroxyl groups; and L is an integer from about 1 to about 200.

Claim 7

A device made from an aliphatic polyoxaamides comprising a first divalent repeating unit of formula I: [X--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)--]I and a second repeating unit selected from the group of formulas consisting of: [--Y--R.sub.17 --].sub.T, II [--O--R.sub.5 C(O)--].sub.B, III ([--O--R.sub.9 --C(O)].sub.P --O--).sub.L G XI and combinations thereof, wherein X and Y are selected from the group consisting of --O-- and --N(R)--, provided that X and Y cannot both be --O--; R, R 1 and R 2 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 3 is selected from the group consisting of an alkylene unit and an oxyalkylene group of the following formula: --[(CH.sub.2).sub.C --O--].sub.D --(CH.sub.2).sub.E -- IV wherein C is an integer in the range of from 2 to about 5, D is an integer in the range of from 0 to about 2,000, and E is an integer in the range of from about 2 to about 5, except when D is zero, in which case E will be an integer in the range of from 2 to 12; R 17 is an alkylene unit containing from 2 to 8 carbon atoms which may have substituted therein an internal ether oxygen, an internal --N(R 18 )-- or an internal --C(O)--N(R 21 )--; T is an integer in the range of from 1 to 2,000; R 18 and R 21 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 5 and R 9 are selected from the group consisting of --C(R 6 )(R 7 )--, --(CH 2 ) 3 --O--, --CH 2 --CH 2 --O--CH 2 --, --CR 8 H--CH 2 --, --(CH 2 ) 4 --, --(CH 2 ) F --O--C(O)-- and --(CH 2 ) K --C(O)--CH 2 --; R 6 and R 7 are independently selected from the group consisting of hydrogen and an alkyl containing from 1 to 8 carbon atoms; R 8 is selected from the group consisting of hydrogen and methyl; F and K are independently selected integer in the range of from 2 to 6; B is an integer in the range of from 1 to n such that the number average molecular weight of formula III is less than about 200,000; P is an integer in the range of from 1 to m such that the number average molecular weight of formula XI is less than about 1,000,000; G represents the residue minus from 1 to L hydrogen atoms from the hydroxyl groups of an alcohol previously containing from 1 to about 200 hydroxyl groups; and L is an integer from about 1 to about 200.

Claim 12

A device coated with an absorbable coating comprising an aliphatic polyoxaamides having a first divalent repeating unit of formula I: [X--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)--]I and a second repeating unit selected from the group of formulas consisting of: [--Y--R.sub.17 --].sub.T, II [--O--R.sub.5 --C(O)--].sub.B, III ([--O--R.sub.9 --C(O)].sub.P --O--).sub.L G XI and combinations thereof, wherein X and Y are selected from the group consisting of --O-- and --N(R)--, provided that X and Y cannot both be --O--; R, R 1 and R 2 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 3 is selected from the group consisting of an alkylene unit and an oxyalkylene group of the following formula: --[(CH.sub.2).sub.C --O--].sub.D --(CH.sub.2).sub.E -- IV wherein C is an integer in the range of from 2 to about 5, D is an integer in the range of from 0 to about 2,000, and E is an integer in the range of from about 2 to about 5, except when D is zero, in which case E will be an integer in the range of from 2 to 12; R 17 is an alkylene unit containing from 2 to 8 carbon atoms which may have substituted therein an internal ether oxygen, an internal --N(R 18 )-- or an internal --C(O)--N(R 21 )--; T is an integer in the range of from 1 to 2,000; R 18 and R 21 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 5 and R 9 are selected from the group consisting of --C(R 6 )(R 7 )--, --(CH 2 ) 3 --O--, --CH 2 --CH 2 --O--CH 2 --, --CR 8 H--CH 2 --, --(CH 2 ) 4 --, --(CH 2 ) F --O--C(O)-- and --(CH 2 ) K --C(O)--CH 2 --; R 6 and R 7 are independently selected from the group consisting of hydrogen and an alkyl containing from 1 to 8 carbon atoms; R 8 is selected from the group consisting of hydrogen and methyl; F and K are independently selected integer in the range of from 2 to 6; B is an integer in the range of from 1 to n such that the number average molecular weight of formula III is less than about 200,000; P is an integer in the range of from 1 to m such that the number average molecular weight of formula XI is less than about 1,000,000; G represents the residue minus from 1 to L hydrogen atoms from the hydroxyl groups of an alcohol previously containing from 1 to about 200 hydroxyl groups; and L is an integer from about 1 to about 200; wherein the inherent viscosity of the polyoxaamide is in the range of from about 0.05 to about 2.0 deciliters per gram (dl/g) as measured in a 0.1 g/dl solution of hexafluoroisopropanol (HFIP) at 25° C.

Claim 13

A device coated with an absorbable coating comprising an aliphatic polyoxaamides having a first divalent repeating unit of formula I: [X--C(O)--C(R.sub.1)(R.sub.2)--O--(R.sub.3)--O--C(R.sub.1)(R.sub.2)--C(O)--]I and a second repeating unit selected from the group of formulas consisting of: [--Y--R.sub.17 --].sub.T, II [--O--R.sub.5 --C(O)--].sub.B, III ([--O--R.sub.9 --C(O)].sub.P --O--).sub.L G XI and combinations thereof, wherein X and Y are selected from the group consisting of --O-- and --N(R)--, provided that X and Y cannot both be --O--; R, R 1 and R 2 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 3 is selected from the group consisting of an alkylene unit and an oxyalkylene group of the following formula: --[(CH.sub.2).sub.C --O--].sub.D --(CH.sub.2).sub.E -- IV wherein C is an integer in the range of from 2 to about 5, D is an integer in the range of from 0 to about 2,000, and E is an integer in the range of from about 2 to about 5, except when D is zero, in which case E will be an integer in the range of from 2 to 12; R 17 is an alkylene unit containing from 2 to 8 carbon atoms which may have substituted therein an internal ether oxygen, an internal --N(R 18 )-- or an internal --C(O)--N(R 21 )--; T is an integer in the range of from 1 to 2,000; R 18 and R 21 are independently selected from the group consisting of hydrogen and an alkyl group containing 1 to 8 carbon atoms; R 5 and R 9 are selected from the group consisting of --C(R 6 )(R 7 )--, --(CH 2 ) 3 --O--, --CH 2 --CH 2 --O--CH 2 --, --CR 8 H--CH 2 --, --(CH 2 ) 4 --, --(CH 2 ) F --O--C(O)-- and --(CH 2 ) K --C(O)--CH 2 --; R 6 and R 7 are independently selected from the group consisting of hydrogen and an alkyl containing from 1 to 8 carbon atoms; R 8 is selected from the group consisting of hydrogen and methyl; F and K are independently selected integer in the range of from 2 to 6; B is an integer in the range of from 1 to n such that the number average molecular weight of formula III is less than about 200,000; P is an integer in the range of from 1 to m such that the number average molecular weight of formula XI is less than about 1,000,000; G represents the residue minus from 1 to L hydrogen atoms from the hydroxyl groups of an alcohol previously containing from 1 to about 200 hydroxyl groups; and L is an integer from about 1 to about 200; wherein the inherent viscosity of the polyoxaamide is in the range of from about 0.05 to about 2.0 deciliters per gram (dl/g) as measured in a 0.1 g/dl solution of hexafluoroisopropanol (HFIP) at 25° C.