Patent US3298698A successfully refreshed from Google Patents.
Patent US5876675A successfully refreshed from Google Patents.
US5876675A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Microfluidic devices and systems
Assignee: Caliper Life Sciences Inc
•
Filing: 1997-08-05
•
Granted: 1999-03-02
•
Expires: 2017-08-05
Abstract
Abstract Microfluidic devices and systems, and particularly, microfluidic devices that are easier to handle by the operator, without damaging, contaminating or otherwise fouling, as a result of manual contact with the device. These microfluidic devices and systems include manual handling structures, to allow handling of the small scale devices with minimal potential for fouling as a result of manual contact with the device.
Inventors
- 👤 Colin B. Kennedy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 22:00
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B01L3/502715; B01L9/00; B01L9/52; B01L9/527; G; G01; G01N; G01N27/00; G01N27/26; G01N27/416; G01N27/447; G01N27/44756; G01N27/44791; B01L2200/00; B01L2200/02; B01L2200/025; B01L2200/08; B01L2200/087; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0816; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0415
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
142 words
A microfluidic apparatus, comprising: a microfluidic device comprising a planar substrate having a first surface and at least two edges, at least two intersecting channels disposed in the substrate, a detection window in the first surface which permits transmission of an optical signal from at least one of the at least two intersecting channels; a holder assembly having a second surface and a cavity disposed therein, the cavity being configured to fixedly receive the microfluidic device; and a manual handling structure integrated with the holder assembly, wherein the manual handling structure is selected from the group consisting of raised ridges disposed on said second surface of the holder assembly and beveled edges positioned on said holder assembly and adjacent to said at least two edges of said substrate of said microfluidic device for gripping said holder assembly without contacting said microfluidic device.
Claim 2
Dependent Claim
142 words
A microfluidic apparatus, comprising: a microfluidic device comprising a planar substrate having a first surface and at least two edges, at least two intersecting channels disposed in the substrate, a detection window in the first surface which permits transmission of an optical signal from at least one of the at least two intersecting channels; a holder assembly having a second surface and a cavity disposed therein, the cavity being configured to fixedly receive the microfluidic device; and a manual handling structure integrated with the holder assembly, wherein the manual handling structure is selected from the group consisting of raised ridges disposed on said second surface of the holder assembly and beveled edges positioned on said holder assembly and adjacent to said at least two edges of said substrate of said microfluidic device for gripping said holder assembly without contacting said microfluidic device.
Claim 3
Dependent Claim
39 words
The microfluidic apparatus of claim 1, wherein the first surface of the microfluidic device comprises a plurality of wells disposed therein, wherein said wells are in fluid communication with at least one of said at least two intersecting channels.
Claim 4
Dependent Claim
16 words
The microfluidic apparatus of claim 1, wherein the first surface of the microfluidic device is hydrophobic.
Claim 5
Dependent Claim
14 words
The microfluidic apparatus of claim 1, wherein the holder assembly comprises a polymeric material.
Claim 6
Dependent Claim
35 words
The microfluidic apparatus of claim 2, wherein the plurality of wells are each configured to receive an electrode, wherein said electrode is positioned to be in electrical contact with a fluid disposed in said wells.
Claim 7
Dependent Claim
132 words
A microfluidic apparatus, comprising: a microfluidic device comprising a substrate having a first surface and at least two edges, at least two intersecting microscale channels disposed in the substrate, a detection window in the first surface which permits transmission of an optical signal from at least one of the at least two intersecting microscale channels; a holder assembly attached to the substrate, the holder assembly having a second surface and a cavity disposed therein, the cavity being configured to fixedly receive the microfluidic device; and a manual handling structure integrated with the holder assembly, wherein the manual handling structure comprises beveled edges positioned on said holder assembly and adjacent to said at least two edges of said substrate of said microfluidic device for gripping said holder assembly without contacting said microfluidic device.
Claim 8
Dependent Claim
132 words
A microfluidic apparatus, comprising: a microfluidic device comprising a substrate having a first surface and at least two edges, at least two intersecting microscale channels disposed in the substrate, a detection window in the first surface which permits transmission of an optical signal from at least one of the at least two intersecting microscale channels; a holder assembly attached to the substrate, the holder assembly having a second surface and a cavity disposed therein, the cavity being configured to fixedly receive the microfluidic device; and a manual handling structure integrated with the holder assembly, wherein the manual handling structure comprises beveled edges positioned on said holder assembly and adjacent to said at least two edges of said substrate of said microfluidic device for gripping said holder assembly without contacting said microfluidic device.
Claim 9
Dependent Claim
39 words
The microfluidic apparatus of claim 6, wherein the first surface of the microfluidic device comprises a plurality of wells disposed therein, wherein said wells are in fluid communication with at least one of said at least two intersecting channels.
Claim 10
Dependent Claim
16 words
The microfluidic apparatus of claim 6, wherein the first surface of the microfluidic device is hydrophobic.
Claim 11
Dependent Claim
14 words
The microfluidic apparatus of claim 6, wherein the holder assembly comprises a polymeric material.
Claim 12
Dependent Claim
35 words
The microfluidic apparatus of claim 7, wherein the plurality of wells are each configured to receive an electrode, wherein said electrode is positioned to be in electrical contact with a fluid disposed in said wells.
References Cited (Backward Citations)
US3939623A
Cited
US4038149A
Cited
US4252132A
Cited
US4390403A
Cited
US4908112A
Cited
US5107987A
Cited
US5160704A
Cited
US4952373A
Cited
US5100627A
Cited
US5126022A
Cited
US5156285A
Cited
US5180480A
Cited
US5279791A
Cited
US5296114A
Cited
US5635403A
Cited
US5296375A
Cited
US5486335A
Cited
US5498392A
Cited
US5726026A
Cited
US5637469A
Cited
US5304487A
Cited
US5635358A
Cited
US5370078A
Cited
US5484731A
Cited
US5599432A
Cited
WO1996004547A1
Cited
US5571410A
Cited
US5593838A
Cited
US5585069A
Cited
US5603351A
Cited
WO1997002357A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-03-01 | 2002-08-31 | 2003-03-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-03-01 | 2006-08-31 | 2007-03-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-03-01 | 2010-08-31 | 2011-03-02 | $7700.00 | Window Closed / Lapsed |