Patent US5913833A successfully refreshed from Google Patents.
US5913833A
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US
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Method and apparatus for obtaining biological fluids
Assignee: Abbott Laboratories
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Filing: 1997-02-07
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Granted: 1999-06-22
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Expires: 2017-02-07
Abstract
Abstract This invention provides a method and apparatus for disrupting the outermost layer of skin, the stratum corneum, to provide access to biological fluid, which can then be used to determine the concentration of glucose in blood. The invention can be used to extract interstitial fluid, blood, and mixtures of interstitial fluid and blood from the body of a human or an animal. The method comprises the steps of (1) attaching a receptacle for collecting biological fluid to the surface of the skin of a patient, (2) introducing an oscillation concentrator attached to an oscillation element into the receptacle, (3) positioning the oscillation concentrator at a desired distance from the surface of the skin, (4) activating the oscillation element to transversely oscillate the attached oscillation concentrator, (5) collecting the biological fluid after a specific period of time, and (6) analyzing the biological fluid for the presence of an analyte.
Inventors
- 👤 Tuan A. Elstrom
- 👤 Eric B. Shain
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 07:20
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/14507; A61B5/1451; A61B5/14514; A61B5/15; A61B5/150007; A61B5/150015; A61B5/150022; A61B5/150053; A61B5/150061; A61B5/150083; A61B5/150343; A61B5/150374; A61B5/150381; A61B5/150412; A61B5/150748; A61B5/150755; A61B5/151; A61B5/15101; A61B5/15103; A61B5/15107; A61B5/15115; A61B5/15121; A61B5/15186; A61M; A61M37/00; A61M37/0092; A61B10/00; A61B10/0045; A61B2010/008; A61B5/14532; A61M2037/0007
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
94 words
A method for obtaining fluid from the body of a patient for diagnostic purposes, said method comprising the steps of: (1) attaching a receptacle to the surface of the skin of a patient, (2) introducing an oscillation concentrator attached to an oscillation element into the receptacle, (3) positioning the oscillation concentrator at a desired distance from the surface of the skin, (4) activating the oscillation element to transversely oscillate the attached oscillation concentrator, (5) collecting the fluid after a specific period of time, and (6) analyzing the fluid for the presence of an analyte.
Claim 2
Independent Claim
94 words
A method for obtaining fluid from the body of a patient for diagnostic purposes, said method comprising the steps of: (1) attaching a receptacle to the surface of the skin of a patient, (2) introducing an oscillation concentrator attached to an oscillation element into the receptacle, (3) positioning the oscillation concentrator at a desired distance from the surface of the skin, (4) activating the oscillation element to transversely oscillate the attached oscillation concentrator, (5) collecting the fluid after a specific period of time, and (6) analyzing the fluid for the presence of an analyte.
Claim 3
Dependent Claim
11 words
The method of claim 1, wherein said fluid is interstitial fluid.
Claim 4
Dependent Claim
10 words
The method of claim 1, wherein said fluid is blood.
Claim 5
Dependent Claim
12 words
The method of claim 1, wherein said receptacle contains a coupling medium.
Claim 6
Dependent Claim
12 words
The method of claim 4, wherein said coupling medium is a liquid.
Claim 7
Dependent Claim
20 words
The method of claim 1, wherein said oscillation concentrator is a needle having a proximal end and a distal end.
Claim 8
Dependent Claim
32 words
The method of claim 1, wherein the distal end of said needle is positioned at a distance ranging from about 0.1 μm to about 1000 μm from the surface of the skin.
Claim 9
Dependent Claim
29 words
The method of claim 1, wherein said oscillation concentrator is caused to oscillate at a frequency of 1×10 2 cycles per second to about 1×10 9 cycles per second.
Claim 10
Dependent Claim
13 words
The method of claim 1, wherein said oscillation element is an ultrasonic horn.
Claim 11
Dependent Claim
13 words
The method of claim 1, wherein said oscillation element is a piezoelectric transducer.
Claim 12
Independent Claim
58 words
An apparatus for obtaining fluid from the body of a patient, said apparatus comprising: (a) an oscillation concentrator having a proximal end and a distal end and having (b) an electromechanical transducer attached at the proximal end of said oscillation concentrator, said oscillation concentrator capable of oscillating in a transverse mode, said oscillation concentrator being of solid construction.
Claim 13
Independent Claim
58 words
An apparatus for obtaining fluid from the body of a patient, said apparatus comprising: (a) an oscillation concentrator having a proximal end and a distal end and having (b) an electromechanical transducer attached at the proximal end of said oscillation concentrator, said oscillation concentrator capable of oscillating in a transverse mode, said oscillation concentrator being of solid construction.
Claim 14
Dependent Claim
13 words
The apparatus of claim 11, wherein said electro-mechanical transducer is an ultrasonic horn.
Claim 15
Dependent Claim
13 words
The apparatus of claim 11, wherein said electromechanical transducer is a piezoelectric crystal.
Claim 16
Dependent Claim
13 words
The apparatus of claim 13, wherein said piezoelectric crystal is excited by voltage.
Claim 17
Dependent Claim
40 words
The apparatus of claim 14, wherein said voltage is applied via electrodes attached to said piezoelectric crystal, thereby causing the crystal to expand and contract in synchrony with the source of excitation, thereby resulting in vibration of said oscillation concentrator.
Claim 18
Dependent Claim
28 words
The apparatus of claim 15, wherein said piezoelectric crystal transfers vibration to said oscillation concentrator, thereby causing freely transverse displacement of the distal end of said oscillation concentrator.
Claim 19
Dependent Claim
20 words
The apparatus of claim 11, wherein said oscillation concentrator is a needle having a proximal end and a distal end.
Claim 20
Independent Claim
83 words
An apparatus for obtaining fluid from the body of a patient, said apparatus comprising: (a) an oscillation concentrator having a proximal end and a distal end and having (b) an electromechanical transducer attached at the proximal end of said oscillation concentrator, said oscillation concentrator capable of oscillating in a transverse mode, wherein said oscillation concentrator is immersed in a reservoir containing a coupling medium in such a manner that the coupling medium is in contact with the surface of human or animal skin.
Claim 21
Independent Claim
83 words
An apparatus for obtaining fluid from the body of a patient, said apparatus comprising: (a) an oscillation concentrator having a proximal end and a distal end and having (b) an electromechanical transducer attached at the proximal end of said oscillation concentrator, said oscillation concentrator capable of oscillating in a transverse mode, wherein said oscillation concentrator is immersed in a reservoir containing a coupling medium in such a manner that the coupling medium is in contact with the surface of human or animal skin.
Claim 22
Dependent Claim
12 words
The apparatus of claim 18, wherein the coupling medium is a liquid.
References Cited (Backward Citations)
US4708127A
Cited
US4948587A
Cited
US4767402A
Cited
US4821740A
Cited
US4953565A
Cited
US5007438A
Cited
US4787888A
Cited
US4780212A
Cited
US5016615A
Cited
US5323769A
Cited
US5115805A
Cited
US5231975A
Cited
EP0736305A2
Cited
US5147291A
Cited
US5076208A
Cited
US5222937A
Cited
US5171215A
Cited
US5405614A
Cited
EP0625360A1
Cited
WO1994008655A2
Cited
US5421816A
Cited
US5267985A
Cited
US5415629A
Cited
US5458140A
Cited
US5445611A
Cited
US5437606A
Cited
WO1998000194A2
Cited
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 2002-06-21 | 2002-12-21 | 2003-06-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-06-21 | 2006-12-21 | 2007-06-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-06-21 | 2010-12-21 | 2011-06-22 | $7700.00 | Window Closed / Lapsed |