US5958741A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Taxol production by a microbe
Assignee: Montana State University – Bozeman
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Filing: 1997-11-26
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Granted: 1999-09-28
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Expires: 2017-11-26
Abstract
Abstract Taxol is produced from taxol-producing microorganisms. Methods of obtaininghe taxol-producing microorganisms are described. Radioactive labelled taxol products and methods for use of the radioactive labelled taxol and for the treatment of leukemia and cancer cells are described.
Inventors
- 👤 Andrea Stierle
- 👤 Donald Stierle
- 👤 Gary Strobel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 18:00
CPC Classifications
C; C12; C12N; C12N1/00; C12N1/14; C12N1/145; C07; C07D; C07D305/00; C07D305/14; C12P; C12P17/00; C12P17/02; C12Q; C12Q1/00; C12Q1/02; C12Q1/04; C12R; C12R2001/00; C12R2001/645; G; G01; G01N; G01N2407/00; G01N2407/02; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/911
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
67 words
A method for the treatment of leukemia, cancer cells or tumors which comprises administering an effective amount of a pharmaceutical composition, which pharmaceutical composition comprises a pharmaceutically effective amount of a taxol composition obtained by culturing a taxane-producing microbe combined with one or more pharmaceutically acceptable inert or physiologically active diluents or adjuvants, wherein said taxane producing microbe is isolated from a tree of the genus Taxus.
Claim 2
Independent Claim
67 words
A method for the treatment of leukemia, cancer cells or tumors which comprises administering an effective amount of a pharmaceutical composition, which pharmaceutical composition comprises a pharmaceutically effective amount of a taxol composition obtained by culturing a taxane-producing microbe combined with one or more pharmaceutically acceptable inert or physiologically active diluents or adjuvants, wherein said taxane producing microbe is isolated from a tree of the genus Taxus.
Claim 3
Dependent Claim
28 words
The method of claim 1, wherein said cancer cells are selected from the group consisting of lung cancer, ovarian cancer, breast cancer, prostate cancer and melanoma cancer cells.
Claim 4
Dependent Claim
31 words
A method according to claim 1, wherein said tree of the genus Taxus is selected from the group consisting of Taxus brevifolia, Taxus baccata, Taxus cuspiduta, Taxus canadensis, and Taxus floridana.
Claim 5
Dependent Claim
12 words
A method according to claim 1, wherein said microbe is a fungus.
Claim 6
Dependent Claim
20 words
A method according to claim 1, wherein said microbe is a fungus having the taxane producing characteristics of Montana BA.
Claim 7
Dependent Claim
27 words
A method according to claim 1, wherein said microbe is an endophytic fungus from the family selected from the group consisting of Fungi imperfecti, hyphomyces, and taxomyces.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-09-27 | 2003-03-29 | 2003-09-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-09-27 | 2007-03-29 | 2007-09-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-09-27 | 2011-03-29 | 2011-09-28 | $7700.00 | Window Closed / Lapsed |