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Radiopaque polymers and methods for preparation thereof

Assignee: Biomat BV
•
Filing: 1995-08-21
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Granted: 2000-03-21
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Expires: 2015-08-21
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Abstract

Abstract The invention is directed to a biomedical polymer having a number average molecular weight of at least 7.500, said polymer being substantially nonporous and having polymerized therein at least one monomer having at least one covalently bound iodine group.

Inventors

  • 👤 Leo Hendrik Koole

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 09:43
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/001; A61K; A61K6/00; A61K6/80; A61K6/884; A61K6/887; A61L27/00; A61L27/14; A61L27/16; A61L27/50; A61L29/00; A61L29/14; A61L29/18; A61L31/00; A61L31/14; A61L31/18

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 133 words
A toy or bone cement being prepared from a radiopaque polymer, said polymer having an average molecular weight of at least 7500, and being substantially non-porous and having polymerized therein at least one monomer having at least one but not more that two covalently bound iodine groups, said monomer having the formula ##STR2## wherein R═H, CH 3 , C 2 H 5 , or another organic substituent, and R'═O--C 6 H 4 I, O--C 6 H 3 I 2 , NH--C 6 H 4 I, NH--C 6 H 3 I 2 , O--CH 2 --CH 2 --C(O)--C 6 H 4 I, O--CH 2 --CH 2 --O--C(O)--C 6 H 3 I 2 , NH--CH 2 --CH 2 --C(O)--C 6 H 4 I or NH--CH 2 --CH 2 --O--C(O)--C 6 H 3 I 2 .
Claim 2
Dependent Claim 133 words
A toy or bone cement being prepared from a radiopaque polymer, said polymer having an average molecular weight of at least 7500, and being substantially non-porous and having polymerized therein at least one monomer having at least one but not more that two covalently bound iodine groups, said monomer having the formula ##STR2## wherein R═H, CH 3 , C 2 H 5 , or another organic substituent, and R'═O--C 6 H 4 I, O--C 6 H 3 I 2 , NH--C 6 H 4 I, NH--C 6 H 3 I 2 , O--CH 2 --CH 2 --C(O)--C 6 H 4 I, O--CH 2 --CH 2 --O--C(O)--C 6 H 3 I 2 , NH--CH 2 --CH 2 --C(O)--C 6 H 4 I or NH--CH 2 --CH 2 --O--C(O)--C 6 H 3 I 2 .
Claim 3
Dependent Claim 23 words
The toy or bone cement of claim 1, wherein at least 20% of the number of polymerized monomers contains said covalently bound iodine.
Claim 4
Dependent Claim 28 words
The toy or bone cement of claim 1, wherein said monomer having iodine covalently bound is a reactive monomer having an iodine containing group attached thereto after polymerization.
Claim 5
Dependent Claim 28 words
The toy or bone cement of claim 2, wherein said monomer having iodine covalently bound is a reactive monomer having an iodine containing group attached thereto after polymerization.
Claim 6
Dependent Claim 58 words
A toy or bone cement being prepared from a polymer, said polymer being a copolymer selected from the group consisting of a first copolymer comprising a mixture of methylmethacrylate and (4-iodophenyl) methacrylate; a second copolymer comprising a mixture of methylmethacrylate, 2- hydroxy ethyl methacrylate, and (4-iodophenyl) methacrylate; and a. third copolymer comprising methylmethacrylate, hydroxy ethylmethacrylate and 2-(4-iodobenzoyl) ethylmethacrylate.
Claim 7
Dependent Claim 58 words
A toy or bone cement being prepared from a polymer, said polymer being a copolymer selected from the group consisting of a first copolymer comprising a mixture of methylmethacrylate and (4-iodophenyl) methacrylate; a second copolymer comprising a mixture of methylmethacrylate, 2- hydroxy ethyl methacrylate, and (4-iodophenyl) methacrylate; and a. third copolymer comprising methylmethacrylate, hydroxy ethylmethacrylate and 2-(4-iodobenzoyl) ethylmethacrylate.

References Cited (Backward Citations)

GB609156A Cited
WO1982001006A1 Cited
US4644025A Cited
US4822721A Cited
US5271923A Cited
US4997894A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-03-21 2003-09-20 2004-03-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-03-21 2007-09-20 2008-03-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-03-21 2011-09-20 2012-03-21 $7700.00 Window Closed / Lapsed

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