Patent US6245215B1 successfully refreshed from Google Patents.
US6245215B1
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Membrane based electrochemical test device and related methods
Assignee: Roche Diabetes Care Inc
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Filing: 1999-09-22
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Granted: 2001-06-12
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Expires: 2019-09-22
Abstract
Abstract An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a counter electrode made of an amorphous semiconductor material. The working electrode is overlaid with a reagent capable of reacting with an analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample. The test device optionally contains a reference electrode made of an amorphous semiconductor material having a reference material on the reference electrode.
Inventors
- 👤 Joel S. Douglas
- 👤 Jeffrey N. Roe
- 👤 John H. Priest
- 👤 David A. Hasker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 10:41
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/26; G; G01; G01N; G01N27/00; G01N27/26; G01N27/28; G01N27/30; G01N27/327; G01N27/3271; G01N27/3272
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
80 words
An electrochemical test device for determining the presence or concentration of an analyte in an aqueous fluid sample, said electrochemical test device comprising: a working electrode comprising an amorphous semiconductor material; an opposing electrode comprising an amorphous semiconductor material; and a reagent capable of reacting with the analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample, said reagent located between the working electrode and the opposing electrode.
Claim 2
Dependent Claim
80 words
An electrochemical test device for determining the presence or concentration of an analyte in an aqueous fluid sample, said electrochemical test device comprising: a working electrode comprising an amorphous semiconductor material; an opposing electrode comprising an amorphous semiconductor material; and a reagent capable of reacting with the analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample, said reagent located between the working electrode and the opposing electrode.
Claim 3
Dependent Claim
25 words
The electrochemical test device of claim 1 , wherein said device further comprises: a non-conductive membrane located between the working electrode and the opposing electrode.
Claim 4
Dependent Claim
19 words
The electrochemical test device of claim 2 , wherein the non-conductive membrane is selected from polysulphone, polyethersulphone, or nylon.
Claim 5
Dependent Claim
33 words
The electrochemical test device of claim 2 , wherein the non-conductive membrane is cased with a tight porous skin on each side and a relatively isotropic matrix is located between the skin surfaces.
Claim 6
Dependent Claim
17 words
The electrochemical test device of claim 1 , wherein the amorphous semiconductor material is amorphous silicon oxide.
Claim 7
Dependent Claim
19 words
The electrochemical test device of claim 1 , wherein the reagent comprises a glucose oxidase and a redox mediator.
Claim 8
Dependent Claim
111 words
An electrochemical test device for determining the presence or concentration of an analyte in an aqueous fluid sample, said electrochemical test comprising: a non-conductive membrane having a first skin and a second skin and a matrix therebetween; a working electrode being affixed to the non-conductive membrane first skin; an opposing electrode affixed to the non-conductive membrane second skin; and a reagent capable of reacting with the analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample, said reagent located between the working electrode and the opposing electrode; wherein at least one of said electrodes comprises an amorphous semiconductor material.
Claim 9
Dependent Claim
111 words
An electrochemical test device for determining the presence or concentration of an analyte in an aqueous fluid sample, said electrochemical test comprising: a non-conductive membrane having a first skin and a second skin and a matrix therebetween; a working electrode being affixed to the non-conductive membrane first skin; an opposing electrode affixed to the non-conductive membrane second skin; and a reagent capable of reacting with the analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample, said reagent located between the working electrode and the opposing electrode; wherein at least one of said electrodes comprises an amorphous semiconductor material.
Claim 10
Dependent Claim
16 words
The electrochemical test device of claim 7 wherein the reagent is imbibed in the membrane matrix.
Claim 11
Dependent Claim
28 words
The electrochemical test device of claim 7 , wherein the opposing electrode is a reference electrode comprising an amorphous semiconductor material affixed to the non-conductive membrane second skin.
Claim 12
Dependent Claim
23 words
The electrochemical test device of claim 9 , wherein at least a portion of the reference electrode is overlaid with a reference material.
Claim 13
Dependent Claim
15 words
The electrochemical test device of claim 10 , wherein said reference material is silver/silver chloride.
Claim 14
Independent Claim
127 words
A method for determining the presence or concentration of an analyte in an aqueous fluid sample, said method comprising: (a) providing an electrochemical device comprising: a working electrode comprising an amorphous semiconductor material; an opposing electrode comprising an amorphous semiconductor material; and a reagent capable of reacting with the analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample, said reagent located between the working electrode and the opposing electrode; (b) applying a sample of an aqueous fluid to the first electrode area of the working electrodes; (c) inserting the electrochemical test device into a meter device; and (d) reading the meter device to determine the presence or concentration of analyte in the fluid sample.
Claim 15
Independent Claim
127 words
A method for determining the presence or concentration of an analyte in an aqueous fluid sample, said method comprising: (a) providing an electrochemical device comprising: a working electrode comprising an amorphous semiconductor material; an opposing electrode comprising an amorphous semiconductor material; and a reagent capable of reacting with the analyte to produce a measurable change in potential which can be correlated to the concentration of the analyte in the fluid sample, said reagent located between the working electrode and the opposing electrode; (b) applying a sample of an aqueous fluid to the first electrode area of the working electrodes; (c) inserting the electrochemical test device into a meter device; and (d) reading the meter device to determine the presence or concentration of analyte in the fluid sample.
Claim 16
Dependent Claim
93 words
A process for preparing an electrochemical test device suitable for determining the presence or concentration of an analyte in an aqueous fluid sample, said process comprising the steps of: providing a non-conductive membrane having a first skin and a second skin and a matrix therebetween; depositing an amorphous semiconductor material on the first skin surface to form a conductive layer which forms a working electrode; depositing an amorphous semiconductor material on the second skin surface to form a conductive layer which forms an opposing electrode; and applying a reagent to imbibe the membrane.
Claim 17
Dependent Claim
93 words
A process for preparing an electrochemical test device suitable for determining the presence or concentration of an analyte in an aqueous fluid sample, said process comprising the steps of: providing a non-conductive membrane having a first skin and a second skin and a matrix therebetween; depositing an amorphous semiconductor material on the first skin surface to form a conductive layer which forms a working electrode; depositing an amorphous semiconductor material on the second skin surface to form a conductive layer which forms an opposing electrode; and applying a reagent to imbibe the membrane.
Claim 18
Dependent Claim
25 words
The process for preparing an electrochemical test device of claim 13 , wherein the reagent is applied through the electrode area of the working electrode.
Claim 19
Dependent Claim
23 words
The process for preparing an electrochemical test device of claim 13 , further comprising: forming a reference electrode on the second skin surface.
Claim 20
Dependent Claim
23 words
The process for preparing an electrochemical test device of claim 13 , wherein the non-conductive membrane is selected from polysulphone, polyethersulphone, or nylon.
Claim 21
Dependent Claim
22 words
The process for preparing an electrochemical test device of claim 13 , wherein the reagent comprises a glucose oxidase and redox mediator.
Claim 22
Dependent Claim
37 words
The process for preparing an electrochemical test device of claim 13 , wherein the non-conductive membrane is cased with a tight porous skin on each side and a relatively isotropic matrix is located between each skin surface.
References Cited (Backward Citations)
US3271591A
Cited
US3983076A
Cited
US4226898A
Cited
US4178415A
Cited
EP0351892A2
Cited
US4938860A
Cited
EP0255291B1
Cited
US5001048A
Cited
US5243516A
Cited
US4963814A
Cited
US4999582A
Cited
US4999632A
Cited
EP0470290A1
Cited
EP0592805A2
Cited
DE4300499A1
Cited
US5437999A
Cited
US5391250A
Cited
EP0710835A2
Cited
US5804048A
Cited
US6001239A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-06-11 | 2004-12-11 | 2005-06-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-06-11 | 2008-12-11 | 2009-06-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-06-11 | 2012-12-11 | 2013-06-12 | $7700.00 | Window Closed / Lapsed |