US7128875B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Signal processing devices comprising biological and bio-mimetic components
Assignee: Individual
•
Filing: 2001-12-18
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Granted: 2006-10-31
•
Expires: 2021-12-18
Abstract
Abstract This invention provides modified phycobilisomes and phycobilisome complexes that are supramolecular complexes with diverse spectral properties, and which may optionally be immobilized on a manufactured solid support. The invention provides a versatile set of highly sensitive signal-generating systems and conjugates that may be used as highly detectable tracers and labels, or in biotransducers comprising phycobilisomes or phycobilisome complexes, and also provides methods for performing specific binding assays using signal-generating systems comprising phycobilisomes as detectable labels. The embodiments of the invention provide the art with an extremely sensitive, nonisotopic detection means for assaying analytes and for sensing molecular events and environmental conditions.
Inventors
- 👤 Roger S. Cubicciotti
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 06:56
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/195; C07K14/405; C07K16/00; C07K16/14; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532; G01N33/533; G01N33/543; G01N33/54306; G01N33/566; G01N33/72; Y; Y10; Y10S; Y10S435/00; Y10S435/963
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
36 words
A system for processing a light signal comprising: conversion means for receiving ultraviolet or visible light and directionally transferring light energy of said light and processing means for receiving and processing said directionally transferred light energy.
Claim 2
Independent Claim
36 words
A system for processing a light signal comprising: conversion means for receiving ultraviolet or visible light and directionally transferring light energy of said light and processing means for receiving and processing said directionally transferred light energy.
Claim 3
Dependent Claim
21 words
The system of claim 1 , wherein said processing means comprises an optical fiber operative to transmit said light signal energy.
Claim 4
Dependent Claim
13 words
The system of claim 1 , wherein said processing means comprises a photosensor.
Claim 5
Dependent Claim
20 words
The system of claim 1 , wherein said conversion means comprises a photon conversion means comprising a supramolecular light-absorbing structure.
Claim 6
Dependent Claim
13 words
The system of claim 1 , wherein said processing means comprises a waveguide.
Claim 7
Dependent Claim
14 words
The system of claim 1 , wherein said processing means comprises an optoelectronic device.
Claim 8
Dependent Claim
14 words
The system of claim 1 , wherein the processing means comprises a photovoltaic cell.
Claim 9
Dependent Claim
17 words
The system of claim 1 , wherein the conversion means comprises phycobiliproteins specifically connected by linker polypeptides.
Claim 10
Independent Claim
35 words
A system for processing electromagnetic radiation comprising: conversion means for receiving electromagnetic radiation and converting said electromagnetic radiation into light energy having a desired property; and processing means for receiving and processing said light energy.
Claim 11
Independent Claim
35 words
A system for processing electromagnetic radiation comprising: conversion means for receiving electromagnetic radiation and converting said electromagnetic radiation into light energy having a desired property; and processing means for receiving and processing said light energy.
Claim 12
Dependent Claim
13 words
The system of claim 9 , wherein said processing means comprises a phycobilisome.
Claim 13
Dependent Claim
14 words
The system of claim 9 , wherein said processing means comprises an optical fiber.
Claim 14
Dependent Claim
13 words
The system of claim 9 , wherein said processing means comprises a waveguide.
Claim 15
Dependent Claim
14 words
The system of claim 9 , wherein said processing means comprises an optoelectronic device.
Claim 16
Dependent Claim
13 words
The system of claim 9 , wherein said processing means comprises a photosensor.
Claim 17
Dependent Claim
15 words
The system of claim 9 , wherein said electromagnetic radiation comprises ultraviolet or visible light.
Claim 18
Dependent Claim
18 words
The system of claim 15 , wherein said light energy is red-shifted relative to the received electromagnetic radiation.
Claim 19
Dependent Claim
10 words
The system of claim 9 , further comprising a transducer.
Claim 20
Dependent Claim
23 words
The system of claim 9 , wherein the conversion means includes a structure comprising a phycobilisome, the phycobilisome comprising two or more phycobiliproteins.
Claim 21
Dependent Claim
20 words
The system of claim 18 , wherein the two or more phycobiliproteins are coupled by one or more linker polypeptides.
Claim 22
Dependent Claim
25 words
The system of claim 19 , wherein the two or more phycobiliproteins are in a particular orientation based on the one or more linker polypeptides.
Claim 23
Dependent Claim
23 words
The system of claim 19 , wherein the particular orientation facilitates energy transfer between at least two of the two or more phycobiliproteins.
Claim 24
Dependent Claim
84 words
The system of claim 1 for processing a light signal comprising: at least one phycobilisome for receiving ultraviolet or visible light and directionally transferring light energy of said light, wherein the at least one phycobilisome comprises at least one of: an isolated, soluble, stabilized phycobilisome; a phycobilisome conjugated to a molecular species selected from the group consisting of ligands, receptors, and signal-generating molecules; and a phycobilisome immobilized on a manufactured solid support; and processing means for receiving and processing said directionally transferred light energy.
Claim 25
Dependent Claim
14 words
The system of claim 22 , wherein the processing means comprises an electronic transducer.
Claim 26
Dependent Claim
14 words
The system of claim 23 , wherein the electronic transducer comprises an optoelectronic transducer.
Claim 27
Dependent Claim
20 words
The system of claim 22 , wherein the at least one phycobilisome comprises at least one isolated, soluble, stabilized phycobilisome.
Claim 28
Dependent Claim
33 words
The system of claim 22 , wherein the at least one phycobilisome comprises at least one phycobilisome conjugated to a molecular species selected from the group consisting of ligands, receptors, and signal-generating molecules.
Claim 29
Dependent Claim
23 words
The system of claim 22 , wherein the at least one phycobilisome comprises at least one phycobilisome immobilized on a manufactured solid support.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2009-10-30 | 2010-05-01 | 2010-10-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2013-10-30 | 2014-05-01 | 2014-10-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2017-10-30 | 2018-05-01 | 2018-10-31 | $7700.00 | Window Closed / Lapsed |