Patent US7544207B2 successfully refreshed from Google Patents.
US7544207B2
Expired / Lapsed
US
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Medical device with bioactive agent
Assignee: Cook Medical Technologies LLC
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Filing: 2005-10-06
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Granted: 2009-06-09
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Expires: 2025-10-06
Abstract
Abstract Medical devices with one or more bioactive agents are provided for regulating fluid flow through a body vessel. Medical devices according to the invention can comprise prosthetic valves that include a bioactive agent.
Inventors
- 👤 Thomas A. Osborne
- 👤 Jacob A. Flagle
- 👤 Brian C. Case
- 👤 Joseph F. Obermiller
- 👤 Ram H. Paul
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 18:16
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2412; A61F2/2418; A61F2/2475; A61F2220/00; A61F2220/0008; A61F2220/0016; A61F2230/00; A61F2230/0002; A61F2230/0017; A61F2230/0026; A61F2230/0063; A61F2230/0067; A61F2230/0073; A61F2230/008; A61F2230/0095; A61F2250/00; A61F2250/0058; A61F2250/0067
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
195 words
A prosthetic valve for selectively permitting fluid flow through a body vessel in a first direction and substantially preventing fluid flow through said body vessel in a second, opposite direction, said prosthetic valve comprising: a support frame having radially expanded and radially compressed configurations; a first bioremodellable leaflet attached to the support frame and including a first base portion attached to the support frame and a first free edge that is moveable within said body vessel; a second bioremodellable leaflet attached to the support frame and including a second base portion attached to the support frame and a second free edge that is moveable within said body vessel; and an antiproliferative agent associated with at least one of the first and second free edges; wherein the first and second free edges cooperatively define a valve orifice that opens and closes in response to movement of the first and second free edges; and wherein the first and second base portions are free of the antiproliferative agent such that remodelling of the at least one free edge with which the antiproliferative agent is associated is delayed with respect to remodelling of the first and second base portions.
Claim 2
Dependent Claim
195 words
A prosthetic valve for selectively permitting fluid flow through a body vessel in a first direction and substantially preventing fluid flow through said body vessel in a second, opposite direction, said prosthetic valve comprising: a support frame having radially expanded and radially compressed configurations; a first bioremodellable leaflet attached to the support frame and including a first base portion attached to the support frame and a first free edge that is moveable within said body vessel; a second bioremodellable leaflet attached to the support frame and including a second base portion attached to the support frame and a second free edge that is moveable within said body vessel; and an antiproliferative agent associated with at least one of the first and second free edges; wherein the first and second free edges cooperatively define a valve orifice that opens and closes in response to movement of the first and second free edges; and wherein the first and second base portions are free of the antiproliferative agent such that remodelling of the at least one free edge with which the antiproliferative agent is associated is delayed with respect to remodelling of the first and second base portions.
Claim 3
Dependent Claim
46 words
The prosthetic valve according to claim 1 , wherein at least one of the first and second leaflets comprises an edge that at least partially defines an opening for permitting a controlled amount of said fluid flow through said body vessel in said second, opposite direction.
Claim 4
Dependent Claim
28 words
The prosthetic valve according to claim 2 , wherein the at least one of the first and second leaflets defines a flap capable of substantially covering the opening.
Claim 5
Dependent Claim
19 words
The prosthetic valve according to claim 1 , wherein the first and second leaflets comprise an extracellular matrix material.
Claim 6
Dependent Claim
18 words
The prosthetic valve according to claim 1 , wherein the first and second leaflets comprise small intestine submucosa.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2012-06-08 | 2012-12-08 | 2013-06-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2016-06-08 | 2016-12-08 | 2017-06-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2020-06-08 | 2020-12-08 | 2021-06-09 | $7700.00 | Window Closed / Lapsed |