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Addition compound of a nucleotide and an amino acid and the use thereof in protection against actinic radiation

Assignee: Port Jervis Laboratories Inc
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Filing: 1974-05-01
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Granted: 1976-02-10
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Expires: 1994-05-01
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Abstract

Abstract An addition compound of one mol of a nucleotide and 1 to 4 mols of an amino carboxylic acid or an amino sulfo acid. The compound is used as an agent for protection against actinic radiation.

Inventors

  • 👤 Otto K. Jacobi

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 15:33
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16; C07H19/20; A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4913; A61K8/492; A61K8/60; A61K8/606; A61Q; A61Q17/00; A61Q17/04; C07H19/06; C07H19/10

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 122 words
A topical composition for protection against actinic radiation, comprising a dermatologically acceptable inert carrier suitable for application to human skin, and having dispersed therein from 0.1% to 99.9% by weight of a compound of the formula: [Nucleoside (PO.sub.3).sub.n.Me.sub.n.sub.+ 1 ]AS.sub.m wherein the nucleoside is a glycoside of a compound selected from the group consisting of adenine, guanine, cytosine, uracil and thymine; Me is a cation selected from the group consisting of hydrogen, an alkali metal, and ammonium; n is an integer from 1 to 3; m is an integer from 1 to (n + 1); and AS is acid having from 1 to 20 carbon atoms and selected from the group consisting of an amino carboxylic acid and an amino sulfo acid.
Claim 2
Dependent Claim 122 words
A topical composition for protection against actinic radiation, comprising a dermatologically acceptable inert carrier suitable for application to human skin, and having dispersed therein from 0.1% to 99.9% by weight of a compound of the formula: [Nucleoside (PO.sub.3).sub.n.Me.sub.n.sub.+ 1 ]AS.sub.m wherein the nucleoside is a glycoside of a compound selected from the group consisting of adenine, guanine, cytosine, uracil and thymine; Me is a cation selected from the group consisting of hydrogen, an alkali metal, and ammonium; n is an integer from 1 to 3; m is an integer from 1 to (n + 1); and AS is acid having from 1 to 20 carbon atoms and selected from the group consisting of an amino carboxylic acid and an amino sulfo acid.
Claim 3
Dependent Claim 15 words
The composition of claim 1, wherein the dermatologically acceptable inert carrier is an aqueous solution.
Claim 4
Dependent Claim 49 words
The composition of claim 1, wherein AS is selected from the group consisting of an alkali metal salt of an amino carboxylic acid, an alkali metal salt of an amino sulfo acid, an ammonium salt of an amino carboxylic acid and an ammonium salt of an amino sulfo acid.
Claim 5
Dependent Claim 11 words
The composition of claim 1, wherein AS is p-amino benzoic acid.
Claim 6
Independent Claim 119 words
A method of protecting human skin against actinic radiation, comprising the step of applying to the skin a dermatologically acceptable inert carrier containing an effective amount of a compound having the formula: [Nucleoside (PO.sub.3).sub.n.Me.sub.n.sub.+ 1 ]AS.sub.m wherein the nucleoside is a glycoside of a compound selected from the group consisting of adenine, guanine, cytosine, uracil and thymine; Me is a cation selected from the group consisting of hydrogen, an alkali metal, and ammonium; n is an integer from 1 to 3; m is an integer from 1 to (n + 1); and AS is an acid having from 1 to 20 carbon atoms and selected from the group consisting of an amino carboxyoic acid and an amino sulfo acid.
Claim 7
Independent Claim 119 words
A method of protecting human skin against actinic radiation, comprising the step of applying to the skin a dermatologically acceptable inert carrier containing an effective amount of a compound having the formula: [Nucleoside (PO.sub.3).sub.n.Me.sub.n.sub.+ 1 ]AS.sub.m wherein the nucleoside is a glycoside of a compound selected from the group consisting of adenine, guanine, cytosine, uracil and thymine; Me is a cation selected from the group consisting of hydrogen, an alkali metal, and ammonium; n is an integer from 1 to 3; m is an integer from 1 to (n + 1); and AS is an acid having from 1 to 20 carbon atoms and selected from the group consisting of an amino carboxyoic acid and an amino sulfo acid.
Claim 8
Dependent Claim 49 words
The method of claim 5, where AS is selected from the group consisting of an alkali metal salt of an amino carboxylic acid, and alkali metal salt of an amino sulfo acid, an ammonium salt of an amino carboxylic acid and an ammonium salt of an amino sulfo acid.
Claim 9
Dependent Claim 10 words
The method of claim 5, wherein AS is p-aminobenzoic acid.

References Cited (Backward Citations)

US3709873A Cited
US3892844A Cited
US3803116A Cited
US3853845A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-02-09 1979-08-11 1980-02-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-02-09 1983-08-11 1984-02-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-02-09 1987-08-11 1988-02-10 $7700.00 Window Closed / Lapsed

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