2-[4-(P-Aminobenzyl)-1-piperazinyl]-8-ethyl-5,8-dihydro-5-oxopyrido[2,3-d]py
Abstract
Abstract 2-[4-(P-Aminobenzyl)-1-piperazinyl]-8-ethyl-5,8-dihydro-5-oxopyrido-[2 ,3-d]pyrimidine-6-carboxylic acid, and its pharmaceutically acceptable salt. This novel compound can be prepared by reacting a compound of the formula <IMAGE> (II) wherein R is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, with a compound of the formula <IMAGE> (III) wherein R1 is an amino group or a group convertible to the amino group, and X is a reactive moiety capable of splitting off together with the hydrogen atom at the 4-position of the 1-piperazinyl group of the compound of the formula (II). Pharmaceutical compositions containing aforesaid compounds as active ingredients are useful for treating a bacterial infection of man and other warm-blooded animals.
Inventors
- 👤 Jun-ichi Matsumoto
Bibliographic Details
Claims Analysis
Total Claims: 8References Cited (Backward Citations)
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