Patent US4148917A successfully refreshed from Google Patents.
US4148917A
Expired / Lapsed
US
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Dermatological compositions
Assignee: Procter and Gamble Co
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Filing: 1978-05-30
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Granted: 1979-04-10
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Expires: 1998-05-30
Abstract
Abstract Compositions for enhancing the penetration of pharmacologically active agents through skin comprising a sugar ester in combination with a sulfoxide or phosphine oxide.
Inventors
- 👤 Donald E. Smith
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 08:55
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K47/00; A61K47/06; A61K47/20; A61K47/24; A61K47/26
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
121 words
A composition in liquid or semi-liquid form adopted to topical application to animal tissue comprising: (1) from about 0.1% to about 15% by weight of a topical anesthetic agent selected from the group consisting of benzocaine, procaine hydrochloride, nupercaine, and pontocaine; (2) from about 0.1% to about 1.0 by weight of a sugar ester selected from the group consisting of sucrose monooctanoate, sucrose monodecanoate, sucrose monolaurate, sucrose myristate, sucrose monopalmitate, sucrose monostearate, sucrose monooleate, and sucrose dioleate; and (3) from about 0.1% to about 10% by weight of a sulfoxide compound selected from the group consisting of octyl methyl sulfoxide, nonyl methyl sulfoxide, decyl methyl sulfoxide, undecyl methyl sulfoxide, dodecyl methyl sulfoxide, 2-hydroxydecyl methyl sulfoxide, 2-hydroxyundecyl methyl sulfoxide, 2-hydroxydodecyl methyl sulfoxide.
Claim 2
Dependent Claim
121 words
A composition in liquid or semi-liquid form adopted to topical application to animal tissue comprising: (1) from about 0.1% to about 15% by weight of a topical anesthetic agent selected from the group consisting of benzocaine, procaine hydrochloride, nupercaine, and pontocaine; (2) from about 0.1% to about 1.0 by weight of a sugar ester selected from the group consisting of sucrose monooctanoate, sucrose monodecanoate, sucrose monolaurate, sucrose myristate, sucrose monopalmitate, sucrose monostearate, sucrose monooleate, and sucrose dioleate; and (3) from about 0.1% to about 10% by weight of a sulfoxide compound selected from the group consisting of octyl methyl sulfoxide, nonyl methyl sulfoxide, decyl methyl sulfoxide, undecyl methyl sulfoxide, dodecyl methyl sulfoxide, 2-hydroxydecyl methyl sulfoxide, 2-hydroxyundecyl methyl sulfoxide, 2-hydroxydodecyl methyl sulfoxide.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-04-09 | 1982-10-09 | 1983-04-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-04-09 | 1986-10-09 | 1987-04-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-04-09 | 1990-10-09 | 1991-04-10 | $7700.00 | Window Closed / Lapsed |