US4279775A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Blood gas control
Assignee: Individual
•
Filing: 1979-12-31
•
Granted: 1981-07-21
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Expires: 1999-12-31
Abstract
Abstract There is disclosed a synthetic liquid control standard for use in the quality assurance of blood gas instrumentation systems which comprises an aqueous solution of a dye buffered to a pH of from about 7.1 to about 7.7 and containing sufficient bicarbonate ion to provide a pCO 2 of from about 20 to about 80, ethylene glycol to provide a viscosity of from about 3 to about 9 centipoises and gaseous oxygen to provide a pO 2 of from about 50 to about 400 retained in a sealed receptacle.
Inventors
- 👤 Allan L. Louderback
- 👤 Paul R. Szatkowski
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 20:52
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; G01N27/00; G01N27/26; G01N27/416; G01N27/4163; G01N2496/00; G01N2496/15; G01N2496/25; G01N2496/30; G01N2496/70; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/102499; Y10T436/108331
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
96 words
A completely synthetic liquid control standard for use in the quality assurance of blood gas instrumentation systems comprising an aqueous solution of a dye buffered to a pH of from about 7.1 to about 7.7 and containing sufficient bicarbonate ion to provide a pCO 2 of from about 20 to about 80, ethylene glycol to provide a viscosity of from about 3 to about 9 centipoises and promote clearing of proteinaceous material from said instrumentation systems and gaseous oxygen to provide a pO 2 of from about 50 to about 400 retained in a sealed receptacle.
Claim 2
Dependent Claim
96 words
A completely synthetic liquid control standard for use in the quality assurance of blood gas instrumentation systems comprising an aqueous solution of a dye buffered to a pH of from about 7.1 to about 7.7 and containing sufficient bicarbonate ion to provide a pCO 2 of from about 20 to about 80, ethylene glycol to provide a viscosity of from about 3 to about 9 centipoises and promote clearing of proteinaceous material from said instrumentation systems and gaseous oxygen to provide a pO 2 of from about 50 to about 400 retained in a sealed receptacle.
Claim 3
Dependent Claim
18 words
The control standard of claim 1 in which the aqueous solution is buffered with N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid buffering agent.
Claim 4
Dependent Claim
20 words
The control standard of claim 1 in which the ethylene glycol provides a viscosity of about 5 to 6 centipoises.
Claim 5
Dependent Claim
44 words
The control standard of claim 1 in which the dye is selected from the group consisting of FD & C Red No. 40, FD & C Yellow No. 5, Peacock Blue and mixtures of said FD & C Yellow No. 5 and Peacock Blue.
Claim 6
Dependent Claim
55 words
The control standard of claim 1 in which the aqueous solution is buffered with N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, the ethylene glycol provides a viscosity of about 5 to 6 centipoises, the dye is FD & C Red No. 40, the pH is about 7.2, the pCO 2 is about 20 and the pO 2 is about 150.
Claim 7
Dependent Claim
55 words
The control standard of claim 1 in which the aqueous solution is buffered with N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, the ethylene glycol provides a viscosity of about 5 to 6 centipoises, the dye is FD & C Yellow No. 5, the pH is about 7.4, the pCO 2 is about 40 and the pO 2 is about 100.
Claim 8
Dependent Claim
51 words
The control standard of claim 1 in which the aqueous solution is buffered with N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, the ethylene glycol provides a viscosity of about 5 to 6 centipoises, the dye is Peacock Blue, the pH is about 7.6, the pCO 2 is about 60 and the pO 2 is about 60.
Claim 9
Dependent Claim
61 words
The control standard of claim 1 in which the aqueous solution is buffered with N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, the ethylene glycol provides a viscosity of about 5 to 6 centipoises, the dye is a mixture of FD & C Yellow No. 5 and Peacock Blue, the pH is about 7.4, the pCO 2 is about 40 and the pO 2 is about 400.
Claim 10
Independent Claim
97 words
The method of making a synthetic liquid control standard for use in the quality assurance of blood gas instrumentation systems and having a viscosity resembling that of blood comprising admixing an aqueous solution of a dye buffered to a pH of from about 7.1 to about 7.7 with sufficient bicarbonate ion to provide a pCO 2 of from about 20 to about 80, ethylene glycol to provide a viscosity of from about 3 to about 9 centipoises and gaseous oxygen to provide a pO 2 of from about 50 to about 400 retained in a sealed receptacle.
Claim 11
Independent Claim
97 words
The method of making a synthetic liquid control standard for use in the quality assurance of blood gas instrumentation systems and having a viscosity resembling that of blood comprising admixing an aqueous solution of a dye buffered to a pH of from about 7.1 to about 7.7 with sufficient bicarbonate ion to provide a pCO 2 of from about 20 to about 80, ethylene glycol to provide a viscosity of from about 3 to about 9 centipoises and gaseous oxygen to provide a pO 2 of from about 50 to about 400 retained in a sealed receptacle.
Claim 12
Dependent Claim
23 words
The control standard of claim 1 in which the receptacle contains a head space filled with a gaseous mixture comprising oxygen and nitrogen.
Claim 13
Dependent Claim
14 words
The control standard of claim 10 in which the gaseous mixture includes carbon dioxide.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-07-20 | 1985-01-19 | 1985-07-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-07-20 | 1989-01-19 | 1989-07-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-07-20 | 1993-01-19 | 1993-07-21 | $7700.00 | Window Closed / Lapsed |