US4483991A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Hypotensive agents
Assignee: Wyeth LLC
•
Filing: 1983-01-17
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Granted: 1984-11-20
•
Expires: 2003-01-17
Abstract
Abstract Compounds of the formula: ##STR1## in which R is alkyl or aralkyl, m and n are 1 or 2, or a pharmaceutically acceptable salt thereof are antihypertensive agents.
Inventors
- 👤 Meier E. Freed
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 14:17
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/02; C07D401/06; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16; C07K; C07K5/00; C07K5/02; C07K5/022; C07K5/0222
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
43 words
A compound of the formula: ##STR5## wherein R is alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 9 carbon atoms, and m and n are, independently, one of the integers 1 or 2, or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim
43 words
A compound of the formula: ##STR5## wherein R is alkyl of 1 to 6 carbon atoms or aralkyl of 7 to 9 carbon atoms, and m and n are, independently, one of the integers 1 or 2, or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim
25 words
A compound of claim 1 of the formula: ##STR6## wherein R is alkyl of 1 to 4 carbon atoms; or a pharmaceutically acceptable salt thereof.
Claim 4
Dependent Claim
16 words
A compound of claim 2 in which the two derivatized carboxyl groups are in trans configuration.
Claim 5
Dependent Claim
14 words
A compound of claim 2 which is 5-ethoxycarbonyl-2-(2'-carboxy-1'-pyrrolidinylcarbonyl)pyrrolidine or a pharmaceutically acceptable salt thereof.
Claim 6
Dependent Claim
14 words
The compound of claim 2 which is trans-5-ethoxycarbonyl-2-[(2'-(S)-carboxy)-1'-pyrrolidinylcarbonyl]pyrrolidine or a pharmaceutically acceptable salt thereof.
Claim 7
Dependent Claim
39 words
A compound of the formula: ##STR7## wherein R is alkyl of 1 to 6 carbon atoms, benzyl, phenethyl or dimethylbenzyl; and m and n are, independently, one of the integers 1 or 2; or a pharmaceutically acceptable salt thereof.
Claim 8
Dependent Claim
39 words
A compound of the formula: ##STR7## wherein R is alkyl of 1 to 6 carbon atoms, benzyl, phenethyl or dimethylbenzyl; and m and n are, independently, one of the integers 1 or 2; or a pharmaceutically acceptable salt thereof.
References Cited (Backward Citations)
US3051722A
Cited
US3586678A
Cited
GB1249643A
Cited
US3804842A
Cited
US3647804A
Cited
US4077951A
Cited
US4374991A
Cited
US4394504A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-11-20 | 1988-05-21 | 1988-11-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-11-20 | 1992-05-21 | 1992-11-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-11-20 | 1996-05-21 | 1996-11-20 | $7700.00 | Window Closed / Lapsed |