US4828705A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pressure-dependent anisotropic-transport membrane system
Assignee: Hymedix International Inc
•
Filing: 1986-10-31
•
Granted: 1989-05-09
•
Expires: 2006-10-31
Abstract
Abstract Pressure-dependent anisotropic behavior is provided by a size selective separation membrane system having two successive porous layers. The first layer is a soft, elastic, effectively porous material, and the second layer is a substantially rigid porous material. When positive pressure presses the first layer against the second layer, the second layer serves as a rigid support, and the first layer is compressed to reduce its effective pore size. The first layer material is characterized by sufficient compressibility, that, when a pressure differential of 100 psi is applied across the thickness of the system, the effective flow rate is reduced by a factor of at least 20 compared to the flow rate when 100 psi is exerted in the opposite direction. A substance can be separated from a liquid mixture using the membrane system by: positioning the second layer of the membrane system in contact with the mixture; exerting pressure on the mixture to force liquid with the substance first through the pores of the rigid layer and the soft layer of the system; and reversing the flow through the membrane system by exerting pressure on the resulting filtrate, in a manner to compress the soft material sufficiently to reduce the pore size to prevent passage of the substance. The membrane system is manufactured by coagulating the layers from polymers in solution.
Inventors
- 👤 Yatin B. Thakore
- 👤 Karen L. Swanson
- 👤 Vladimir A. Stoy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 03:11
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/28; A61K9/2806; A61K9/2833; A61K9/284; B; B01; B01D; B01D61/00; B01D61/14; B01D61/149; B01D69/00; B01D69/02; B01D69/12; B01D69/1214
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
249 words
A method of separating a substance from a fluid mixture by using a pressure-dependent anisotropic-transport membrane system, comprising the steps of: (a) positioning said fluid mixture in contact with a rigid layer of an effectively porous component of a pressure-dependent anisotropic-transport membrane system; (b) exerting a pressure gradient across said pressure-dependent anisotropic-transport membrane system, whereby: (i) said pressure gradient causing a higher pressure to act against said rigid layer to force said fluid containing said substance through said rigid layer, (ii) said pressure gradient causing a lower pressure on the other side of said rigid layer, said pressure gradient acting on a soft elastic layer of reversibly compressible and effectively porous component of said pressure-dependent anisotropic-transport membrane system, said pressure gradient causing said soft elastic layer to reversibly expand away from said rigid layer to increase the effective pore size of the soft elastic layer and allow the fluid containing the substance to pass through the soft elastic layer, (c) reversing the pressure gradient across the pressure-dependent anisotropic-transport membrane system, said reversed pressure gradient causing a higher pressure to be exerted against the elastic layer, reversibly compressing the soft elastic layer against the rigid layer reducing the effective pore size of the soft elastic layer sufficiently to allow the passage of the fluid through the soft elastic layer and then through the rigid layer, but preventing the passage of the substance through the soft elastic layer, whereby the substance is retained on the side of the soft elastic layer.
Claim 2
Independent Claim
249 words
A method of separating a substance from a fluid mixture by using a pressure-dependent anisotropic-transport membrane system, comprising the steps of: (a) positioning said fluid mixture in contact with a rigid layer of an effectively porous component of a pressure-dependent anisotropic-transport membrane system; (b) exerting a pressure gradient across said pressure-dependent anisotropic-transport membrane system, whereby: (i) said pressure gradient causing a higher pressure to act against said rigid layer to force said fluid containing said substance through said rigid layer, (ii) said pressure gradient causing a lower pressure on the other side of said rigid layer, said pressure gradient acting on a soft elastic layer of reversibly compressible and effectively porous component of said pressure-dependent anisotropic-transport membrane system, said pressure gradient causing said soft elastic layer to reversibly expand away from said rigid layer to increase the effective pore size of the soft elastic layer and allow the fluid containing the substance to pass through the soft elastic layer, (c) reversing the pressure gradient across the pressure-dependent anisotropic-transport membrane system, said reversed pressure gradient causing a higher pressure to be exerted against the elastic layer, reversibly compressing the soft elastic layer against the rigid layer reducing the effective pore size of the soft elastic layer sufficiently to allow the passage of the fluid through the soft elastic layer and then through the rigid layer, but preventing the passage of the substance through the soft elastic layer, whereby the substance is retained on the side of the soft elastic layer.
Claim 3
Dependent Claim
69 words
The method recited in claim 1, wherein step (c) of reversing said pressure gradient further includes controlling said pressure gradient exerted across the soft elastic layer to a predetermined range which maintains an effective pore size in the soft elastic layer and prevents the passage of said substance through the soft elastic layer but allows passage of any other substance smaller than said substance through the soft elastic layer.
Claim 4
Dependent Claim
36 words
The method recited in claim 2, wherein said mixture includes a second substance too large to pass through the membrane system in either direction, whereby said method effectively separates said first substance from said second substance.
Claim 5
Dependent Claim
79 words
The method recited in claim 1, wherein the pressure gradient across said pressure-dependent anisotropic-transport membrane system is periodically reversed, whereby during application of a higher pressure to said soft elastic layer said fluid flowing through said pressure-dependent anisotropic-transport membrane system disrupts the build-up of substance on said rigid layer, and whereby during application of higher pressure to said rigid layer said fluid flowing through said pressure-dependent anisotropic-transport membrane system disrupts the build-up of substance on said soft elastic layer.
Claim 6
Independent Claim
89 words
A method for manufacturing pressure-dependent anisotropic-transport membrane system having a rigid substantially porous polymeric layer interfacing with a soft elastic substantially porous reversibly compressible polymeric layer, comprising the steps of: (a) dissolving a soft elastic polymer and a rigid polymer in solvent; (b) coagulating said polymers by contacting the solution with a fluid bath in which one of the polymers is more soluble than the other polymer, whereby the first, less soluble polymer coagulates as a first layer and a second more soluble polymer coagulates as a second layer.
Claim 7
Independent Claim
89 words
A method for manufacturing pressure-dependent anisotropic-transport membrane system having a rigid substantially porous polymeric layer interfacing with a soft elastic substantially porous reversibly compressible polymeric layer, comprising the steps of: (a) dissolving a soft elastic polymer and a rigid polymer in solvent; (b) coagulating said polymers by contacting the solution with a fluid bath in which one of the polymers is more soluble than the other polymer, whereby the first, less soluble polymer coagulates as a first layer and a second more soluble polymer coagulates as a second layer.
Claim 8
Dependent Claim
13 words
The method of claim 5, wherein said fluid bath is an aqueous fluid.
Claim 9
Dependent Claim
26 words
The method of claim 6, wherein the layers are coagulated by spreading the solution on a substrate and then contracting the substrate with said fluid bath.
Claim 10
Dependent Claim
85 words
The method of claim 5, further comprising the steps of: (a) dissolving said first polymer in a first solution, (b) dissolving said second polymer in a second solution, (c) spreading the first solution on a substrate and coagulating the first solution with a non-solvent of said first polymer to form a first layer, and (d) spreading the second solution on the first layer and coagulating the second solution with a non-solvent of said second polymer to form adhering layers of the first and second polymers.
References Cited (Backward Citations)
US3556305A
Cited
US3556992A
Cited
US3593852A
Cited
US4545910A
Cited
US4095877A
Cited
US4107121A
Cited
US4379874A
Cited
US4659474A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-05-08 | 1992-11-07 | 1993-05-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-05-08 | 1996-11-07 | 1997-05-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-05-08 | 2000-11-07 | 2001-05-09 | $7700.00 | Window Closed / Lapsed |