Patent US4886786A successfully refreshed from Google Patents.
US4886786A
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Additive for irrigation solution or surgical solution
Assignee: Individual
•
Filing: 1988-02-02
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Granted: 1989-12-12
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Expires: 2008-02-02
Abstract
Abstract An additive for intraocular irrigation solution or surgical solution which provides the anterior chamber and posterior chamber of the eye with protection during surgical procedures that require irrigation. The additive for the solutions is composed of a balanced salt solution containing dextrose supplemented with chondroitin sulfate. Other chemical compositions can supplement the additive.
Inventors
- 👤 Richard L. Lindstrom
- 👤 Debra L. Skelnik
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 08:24
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
50 words
An aqueous supplementary concentrate for addition to Balanced Salt Solution for Ringer's Solution to form a surgical solution, the concentrate consisting essentially of effective amounts of: a. water; b. a glycosaminogycan; c. an antioxidant; d. dextrose or a pyruvate, or both; e. an amino acid; and, f. a bicarbonate buffer.
Claim 2
Dependent Claim
50 words
An aqueous supplementary concentrate for addition to Balanced Salt Solution for Ringer's Solution to form a surgical solution, the concentrate consisting essentially of effective amounts of: a. water; b. a glycosaminogycan; c. an antioxidant; d. dextrose or a pyruvate, or both; e. an amino acid; and, f. a bicarbonate buffer.
Claim 3
Dependent Claim
40 words
The concentration of claim 1 wherein (b) is chondroitin sulfate, dermatan sulfate, haparan sulfate, heparin sulfate or hyaluorinic acid; (c) is 2-mercaptoethanol, ascorbic acid or glutathione; (d) is a pyruvate or dextrose; and (e) is cystine, inosine, adenine or adenosin.
Claim 4
Dependent Claim
31 words
The concentrate of claims 1 or 2 wherein the components are present in the following concentrations: (b) 0.001-550 mg/ml (c) 0.1-10 mM (d) 0.5-100 mM (e) 0.1-50 mM (f) 0.01-100 mM
Claim 5
Dependent Claim
48 words
A supplementary concentrate for addition to Balanced Salt Solution or Ringer's Solution to form a surgical solution, the concentrate consisting essentially of: a. water; b. chondroitin sulfate, 0.001-550 mg/ml; c. 2-mercaptoethanol, 0.1-10 mM; d. a pyruvate, 0.5-100 mM; e. cystine, 0.1-50 mM; and, f. sodium bicarbonate, 0.01-100 mM
Claim 6
Dependent Claim
48 words
A supplementary concentrate for addition to Balanced Salt Solution or Ringer's Solution to form a surgical solution, the concentrate consisting essentially of: a. water; b. chondroitin sulfate, 0.001-550 mg/ml; c. 2-mercaptoethanol, 0.1-10 mM; d. a pyruvate, 0.5-100 mM; e. cystine, 0.1-50 mM; and, f. sodium bicarbonate, 0.01-100 mM
Claim 7
Dependent Claim
22 words
A concentrate according to any one of claims 1 and 4 additionally containing at least one cell growth factor or growth supplement.
Claim 8
Dependent Claim
37 words
The concentrate of claim 5 in which the factor or supplement is laminin, fibronectin, fibroblastic growth factor, endothelial cell growth supplement, urogastrone, epidermal growth factor, bovine pituitary extract, insulin, IV collagen, enactin, ethanolamine, phosphoethanolamine or sialic acid.
References Cited (Backward Citations)
US4024237A
Cited
US4725586A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-12-11 | 1993-06-12 | 1993-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-12-11 | 1997-06-12 | 1997-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-12-11 | 2001-06-12 | 2001-12-12 | $7700.00 | Window Closed / Lapsed |