Patent US5032393A successfully refreshed from Google Patents.
US5032393A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Drug adsorbates
Assignee: Glaxo Group Ltd
•
Filing: 1989-05-10
•
Granted: 1991-07-16
•
Expires: 2009-05-10
Abstract
Abstract The bitter taste of ranitidine may be masked by forming an adsorbate with a synthetic cation exchange resin. The adsorbate is particularly suitable for use in pharmaceutical compositions for oral administration such as chewable or suckable tablets, granules and aqueous or non-aqueous suspensions.
Inventors
- 👤 Stephen J. Douglas
- 👤 Fiona R. Bird
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 14:07
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/34; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K47/585; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0056; A61P; A61P1/00; A61P1/04; A61P29/00
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
39 words
A resin adsorbate which comprises a complex formed between ranitidine and a synthetic cation exchange resin, wherein said syntheticati on exchange resin is selected from copolymer of styrene and divinylbenzene which are sulphonated, and copolymers of methacrylic and divinylbenzene.
Claim 2
Dependent Claim
39 words
A resin adsorbate which comprises a complex formed between ranitidine and a synthetic cation exchange resin, wherein said syntheticati on exchange resin is selected from copolymer of styrene and divinylbenzene which are sulphonated, and copolymers of methacrylic and divinylbenzene.
Claim 3
Dependent Claim
30 words
A resin adsorbate according to claim 1 in which said synthetic cation exchange resin is in acid form or is in the form of a salt with an alkali metal.
Claim 4
Dependent Claim
23 words
A resin adsorbate according to claim 1 in which said synthetic cation exchange resin is a methacrylic aciddivinylbenzene resin in free acid form.
Claim 5
Dependent Claim
27 words
A resin adsorbate according to claim 1 containing 5 to 70% ranitidine expressed as the weight of ranitidine free base based on the weight of resin adsorbate.
Claim 6
Dependent Claim
13 words
A resin adsorbate according to claim 5 containing 20 to 30% of ranitidine.
Claim 7
Dependent Claim
12 words
A resin adsorbate according to claim 5 containing 15 to 55% ranitidine.
Claim 8
Dependent Claim
27 words
A resin adsorbate according to claim 4 containing 5 to 70% ranitidine expressed as the weight of ranitidine free base based on the weight of resin adsorbate.
Claim 9
Dependent Claim
12 words
A resin adsorbate according to claim 8 containing 20 to 30% ranitidine.
Claim 10
Dependent Claim
12 words
A resin adsorbate according to claim 8 containing 15 to 55% ranitidine.
Claim 11
Dependent Claim
18 words
A resin adsorbate according to claim 1 which is substantially free of the bitter taste associated with ranitidine.
Claim 12
Dependent Claim
18 words
A resin adsorbate according to claim 4 which is substantially free of the bitter taste associated with ranitidine.
References Cited (Backward Citations)
US2828207A
Cited
US2990332A
Cited
US2970053A
Cited
US3138525A
Cited
US3949068A
Cited
GB1218102A
Cited
US4585790A
Cited
US4788055A
Cited
JPS6369038A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-07-15 | 1995-01-14 | 1995-07-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-07-15 | 1999-01-14 | 1999-07-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-07-15 | 2003-01-14 | 2003-07-16 | $7700.00 | Window Closed / Lapsed |