Patent US5059423A successfully refreshed from Google Patents.
US5059423A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Delivery system comprising biocompatible beneficial agent formulation
Assignee: Alza Corp
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Filing: 1990-04-23
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Granted: 1991-10-22
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Expires: 2010-04-23
Abstract
Abstract A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
Inventors
- 👤 Judy A. Magruder
- 👤 James B. Eckenhoff
- 👤 Richard Cortese
- 👤 Jeremy C. Wright
- 👤 John R. Peery
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 21:37
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
124 words
A dispenser for delivering a beneficial agent to an animal, the dispenser comprising: a wall surrounding an internal lumen comprising a pair of ends in mated contact to form a closed dispenser, said wall comprising a section that substantially limits the passage of fluid into the lumen and a section that permits the passage of fluid into the lumen; a beneficial agent in the lumen comprising the section that limits the passage of fluid; an expandable hydrophilic hydrogel selected from the groups consisting of cross-linked and non-crosslinked hydrogels which exhibit a 2 to 50 fold volume increase in the lumen in the section that permits the passage of fluid; and, an exit passageway in the dispenser for delivering the beneficial agent to the animal.
Claim 2
Dependent Claim
124 words
A dispenser for delivering a beneficial agent to an animal, the dispenser comprising: a wall surrounding an internal lumen comprising a pair of ends in mated contact to form a closed dispenser, said wall comprising a section that substantially limits the passage of fluid into the lumen and a section that permits the passage of fluid into the lumen; a beneficial agent in the lumen comprising the section that limits the passage of fluid; an expandable hydrophilic hydrogel selected from the groups consisting of cross-linked and non-crosslinked hydrogels which exhibit a 2 to 50 fold volume increase in the lumen in the section that permits the passage of fluid; and, an exit passageway in the dispenser for delivering the beneficial agent to the animal.
Claim 3
Independent Claim
150 words
A method for delivering a somatotropin to a hog, wherein the method comprises: (a) implanting in the hog a dispenser comprising: (1) a wall that surrounds an internal lumen, said wall (i) comprising at least in part a section that restricts the passage of fluid into the lumen, and (ii) comprising at least in part a section that permits the passageway of fluid into the lumen; (2) a porcine somatotropin in the lumen in section (i); (3) an osmotically effective solute in the lumen in section (ii); (4) an inert partition between the porcine somatotropin and the osmotically effective solute in the lumen; (5) at least one exit passageway in the dispenser for delivering the porcine somatotropin from the dispenser; and, (b) delivering the porcine somatotropin by the osmotically effective solute mixing with the fluid and increasing in volume, thereby pushing the porcine somatotropin through a passageway to the hog.
Claim 4
Independent Claim
150 words
A method for delivering a somatotropin to a hog, wherein the method comprises: (a) implanting in the hog a dispenser comprising: (1) a wall that surrounds an internal lumen, said wall (i) comprising at least in part a section that restricts the passage of fluid into the lumen, and (ii) comprising at least in part a section that permits the passageway of fluid into the lumen; (2) a porcine somatotropin in the lumen in section (i); (3) an osmotically effective solute in the lumen in section (ii); (4) an inert partition between the porcine somatotropin and the osmotically effective solute in the lumen; (5) at least one exit passageway in the dispenser for delivering the porcine somatotropin from the dispenser; and, (b) delivering the porcine somatotropin by the osmotically effective solute mixing with the fluid and increasing in volume, thereby pushing the porcine somatotropin through a passageway to the hog.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-10-21 | 1995-04-22 | 1995-10-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-10-21 | 1999-04-22 | 1999-10-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-10-21 | 2003-04-22 | 2003-10-22 | $7700.00 | Window Closed / Lapsed |