Patent US6530951B1 successfully refreshed from Google Patents.
US6530951B1
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US
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Silver implantable medical device
Assignee: Cook Medical Technologies LLC
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Filing: 1997-10-23
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Granted: 2003-03-11
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Expires: 2017-10-23
Abstract
Abstract A silver implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one layer 18 of a bioactive material posited on one surface of structure 12; and at least one porous layer 20 posited over the bioactive material layer 18 posited on one surface of structure 12 and the bioactive-material-free surface. Also included is a layer or impregnation of silver 45. Preferably, the structure 12 is a coronary stent. The porous layer 20 is comprised of a polymer applied preferably by vapor or plasma deposition and provides a controlled release of the bioactive material. It is particularly preferred that the polymer is a polyamide, parylene or a parylene derivative, which is deposited without solvents, heat or catalysts, merely by condensation of a monomer vapor. Silver is included as a base material, coating or included in a carrier, drug, medicament material utilized with the implantable stent.
Inventors
- 👤 Brian L. Bates
- 👤 Neal E. Fearnot
- 👤 Thomas G. Kozma
- 👤 Thomas A. Osborne
- 👤 Anthony O. Ragheb
- 👤 Joseph W. Roberts
- 👤 William D. Voorhees, III
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 20:49
CPC Classifications
A; A61; A61L; A61L29/00; A61L29/14; A61L29/16; A61L27/00; A61L27/28; A61L27/30; A61L27/306; A61L27/50; A61L27/54; A61L29/08; A61L29/10; A61L29/106; A61L31/00; A61L31/08; A61L31/082; A61L31/088; A61L31/14; A61L31/16; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/104; A61L2300/40; A61L2300/404; A61L2300/416; A61L2300/42; A61L2300/60; A61L2300/606; A61L2300/608; A61L2300/61
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
55 words
An implantable medical device, comprising: a structure adapted for introduction into a patient, the structure being comprised of a base material and a layer of elemental silver having a uniform thickness posited on said base material, the elemental silver layer further having a specific surface energy density of about 20 to 30 dyne per centimeter.
Claim 2
Dependent Claim
55 words
An implantable medical device, comprising: a structure adapted for introduction into a patient, the structure being comprised of a base material and a layer of elemental silver having a uniform thickness posited on said base material, the elemental silver layer further having a specific surface energy density of about 20 to 30 dyne per centimeter.
Claim 3
Dependent Claim
20 words
The device according to claim 1 , wherein said layer of elemental silver is posited directly on said base material.
Claim 4
Dependent Claim
32 words
The device according to claim 1 , wherein a non-silver metal or metal alloy layer is posited on said base material and said layer of silver is posited on said non-silver layer.
Claim 5
Dependent Claim
26 words
The device according to claim 1 , wherein said base material comprises a polymer coating and said elemental silver layer is posited on said polymer coating.
Claim 6
Dependent Claim
26 words
The device according to claim 4 , wherein a non-silver metal or metal alloy layer is posited between said polymer coating and said elemental silver layer.
Claim 7
Dependent Claim
68 words
An implantable medical device, comprising: a structure adapted for introduction into a patient, the structure being comprised of a base material wherein elemental silver, silver ions or a combination thereof in a bioactive effective amount is impregnated into a surface matrix of the base material, the elemental silver, silver ions, or combination thereof further have a specific surface energy density of about 20 to 30 dyne per centimeter.
Claim 8
Dependent Claim
68 words
An implantable medical device, comprising: a structure adapted for introduction into a patient, the structure being comprised of a base material wherein elemental silver, silver ions or a combination thereof in a bioactive effective amount is impregnated into a surface matrix of the base material, the elemental silver, silver ions, or combination thereof further have a specific surface energy density of about 20 to 30 dyne per centimeter.
Claim 9
Dependent Claim
16 words
The device according to claim 6 , wherein the structure is configured as a vascular stent.
Claim 10
Dependent Claim
53 words
The device according to claim 6 , wherein the structure is configured as at least one of: a stent, a vascular or other graft, a vascular or other graft in combination with a stent, heart valve, an orthopedic device, appliance, implant or replacement, or portion thereof; or a portion of any of these.
Claim 11
Dependent Claim
13 words
The device according to claim 6 , wherein the base material is biocompatible.
Claim 12
Dependent Claim
112 words
The device according to claim 6 , wherein the base material of the structure includes at least one of: stainless steel, tantalum, titanium, Nitinol, gold, platinum, inconel, iridium, silver, tungsten, or another biocompatible metal, or alloys of any of these; carbon or carbon fiber; cellulose acetate, cellulose nitrate, silicone, polyethylene teraphthalate, polyurethane, polyamide, polyester, polyorthoester, polyanhydride, polyether sulfone, polycarbonate, polypropylene, high molecular weight polyethylene, polytetrafluoroethylene, or another biocompatible polymeric material, or mixtures or copolymers thereof; polylactic acid, polyglycolic acid or copolymers thereof, a polyanhydride, polycaprolactone, polyhydroxy-butyrate valerate or another biodegradable polymer, or mixtures or copolymers of these; a protein, an extracellular matrix component, collagen, fibrin or another biologic agent; or mixture thereof.
Claim 13
Dependent Claim
16 words
The device according to claim 6 , wherein said device is a balloon expandable vascular stent.
Claim 14
Dependent Claim
15 words
The device according to claim 6 , wherein said device is a self-expanding vascular stent.
Claim 15
Dependent Claim
54 words
An implantable vascular device, comprising: stent structure adapted for introduction into a vascular system of a patient, the stent structure comprising elemental silver or silver alloys having at least 50% by weight silver, the elemental silver, or silver alloys further have a specific surface energy density of about 20 to 30 dyne per centimeter.
Claim 16
Dependent Claim
54 words
An implantable vascular device, comprising: stent structure adapted for introduction into a vascular system of a patient, the stent structure comprising elemental silver or silver alloys having at least 50% by weight silver, the elemental silver, or silver alloys further have a specific surface energy density of about 20 to 30 dyne per centimeter.
Claim 17
Dependent Claim
38 words
The vascular device according to claim 13 , wherein the device is produced from an alloy of silver and copper where the copper in the alloy can range from about 15% by weight to about 50% by weight.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-03-10 | 2006-09-09 | 2007-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-03-10 | 2010-09-09 | 2011-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-03-10 | 2014-09-09 | 2015-03-11 | $7700.00 | Window Closed / Lapsed |