US4675182A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Complexes of prostaglandins
Assignee: Bayer AG
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Filing: 1984-01-27
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Granted: 1987-06-23
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Expires: 2004-01-27
Abstract
Abstract The present invention relates to complexes of prostaglandins and crosspovidone, pre-pasted starch or dextrans, a process for the preparation of these complexes, their use in or as medicaments, and medicaments or pharmaceutical formulations containing complexes of prostaglandins or crosspovidone, pre-pasted starch or dextrans.
Inventors
- 👤 Bernhard Streuff
- 👤 Detlef Mathes
- 👤 Bernd Schade
- 👤 Ulrich Schorsch
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/557; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K47/61; A61K9/00; A61K9/14
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
19 words
A complex of 16-methyl-1-11α,16RS-Trihydroxyprost-13E-en-9-one of the formula (I) ##STR5## with crosspovidone, having a prostaglandin content of 0.01-50% by weight.
Claim 2
Dependent Claim
19 words
A complex of 16-methyl-1-11α,16RS-Trihydroxyprost-13E-en-9-one of the formula (I) ##STR5## with crosspovidone, having a prostaglandin content of 0.01-50% by weight.
Claim 3
Dependent Claim
15 words
A complex of claim 1 having a prostaglandin content of 0.1 to 10% by weight.
Claim 4
Dependent Claim
15 words
A complex of claim 1 having a prostaglandin content of 0.2 to 1.0% by weight.
Claim 5
Dependent Claim
45 words
A pharmaceutical composition useful in the treatment of hypertension, bronchial asthma, gastrointestinal ulcers and thrombosis and for inducing labor and abortion in mammals containing as an active ingredient, a pharmaceutically effective amount of a complex according to claim 1 together with an inert pharmaceutical carrier.
Claim 6
Dependent Claim
16 words
A composition of claim 4 in the form of a sterile or physiologically isotonic aqueous solution.
Claim 7
Dependent Claim
42 words
A medicament in dosage unit form useful in the treatment of hypertension, bronchial asthma, gastrointestinal ulcers and thrombosis and for inducing labor and abortion in mammals comprising a pharmaceutically effective amount of complex according to claim 1 and an inert pharmaceutical carrier.
Claim 8
Dependent Claim
17 words
A medicament of claim 6 in the form of tablets, pills, dragees, capsules, ampouls, suppositories or creams.
Claim 9
Dependent Claim
41 words
A method of combatting gastrointestinal ulcers in warm-blooded animals which comprises administering to the animals an effective amount of an active complex according to claim 1 either alone or in admixture with a diluent or in the form of a medicament.
Claim 10
Dependent Claim
16 words
A method according to claim 8 in which the active complex is administered orally or parenterally.
Claim 11
Dependent Claim
20 words
A medicament containing 16-methyl-1,11,16-RS-Trihydroxyprost-13E-en-9one of the formula ##STR6## bonded to crossprovidone in an amount of 0.001 to 10 by weight.
Claim 12
Dependent Claim
20 words
A medicament containing 16-methyl-1,11,16-RS-Trihydroxyprost-13E-en-9one of the formula ##STR6## bonded to crossprovidone in an amount of 0.001 to 10 by weight.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-22 | 1990-12-22 | 1991-06-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-22 | 1994-12-22 | 1995-06-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-22 | 1998-12-22 | 1999-06-23 | $7700.00 | Window Closed / Lapsed |