Patent US6982027B2 successfully refreshed from Google Patents.
US6982027B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biosensor
Assignee: Arkray Inc
•
Filing: 2001-10-25
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Granted: 2006-01-03
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Expires: 2021-10-25
Abstract
Abstract A biosensor is provided, which can measure an analyte in a sample with high precision. The biosensor is produced by disposing a electrode system including a working electrode 12 and a counter electrode 13 on a substrate 11 , and then forming a reagent layer 16 containing a reagent and particulates on the electrode system. The influence of the impurities in the sample on the electrode system can be eliminated by the particulates. The average particle diameter of the particulates preferably is in the range from 0.1 to 45 μm.
Inventors
- 👤 Yuji Yagi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 04:21
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/002
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
67 words
A biosensor comprising a substrate, a reagent layer containing a reagent, and an electrode system including a working electrode and a counter electrode, the electrode system being disposed on the substrate, and the reagent layer being formed on the electrode system, wherein the reagent layer further comprises particulates, and an inorganic gel-containing layer containing an inorganic gel is formed between the electrode system and the reagent layer.
Claim 2
Dependent Claim
67 words
A biosensor comprising a substrate, a reagent layer containing a reagent, and an electrode system including a working electrode and a counter electrode, the electrode system being disposed on the substrate, and the reagent layer being formed on the electrode system, wherein the reagent layer further comprises particulates, and an inorganic gel-containing layer containing an inorganic gel is formed between the electrode system and the reagent layer.
Claim 3
Dependent Claim
15 words
The biosensor according to claim 1 , wherein the reagent layer is a single layer.
Claim 4
Dependent Claim
28 words
The biosensor according to claim 1 , wherein the reagent layer is a laminate comprising a reagent-containing layer containing the reagent and a particulate-containing layer containing the particulates.
Claim 5
Dependent Claim
21 words
The biosensor according to claim 3 , wherein the particulate-containing layer is formed on the electrode system via the reagent-containing layer.
Claim 6
Dependent Claim
16 words
The biosensor according to claim 1 , wherein the reagent layer further comprises an inorganic gel.
Claim 7
Dependent Claim
17 words
The biosensor according to claim 5 , wherein the inorganic gel is a gel of clay mineral.
Claim 8
Dependent Claim
14 words
The biosensor according to claim 6 , wherein the clay mineral is expansive phyllosilicate.
Claim 9
Dependent Claim
21 words
The biosensor according to claim 1 , wherein a surfactant-containing layer containing a surfactant further is formed on the reagent layer.
Claim 10
Dependent Claim
24 words
The biosensor according to claim 1 , wherein an average particle diameter of the particulates is in a range from 0.1 to 45 μm.
Claim 11
Dependent Claim
23 words
The biosensor according to claim 1 , wherein particle size distribution of the particulates is in a range from 0.01 to 100 μm.
Claim 12
Dependent Claim
12 words
The biosensor according to claim 1 , wherein the particulates are spherical.
Claim 13
Dependent Claim
16 words
The biosensor according to claim 1 , wherein the particulates are formed of a polymer compound.
Claim 14
Dependent Claim
22 words
The biosensor according to claim 12 , wherein the polymer compound does not contain an impurity causing electrolysis and is electrochemically inactive.
Claim 15
Dependent Claim
13 words
The biosensor according to claim 12 , wherein the polymer compound is water-insoluble.
Claim 16
Dependent Claim
42 words
The biosensor according to claim 12 , wherein the polymer compound is a polymer or a copolymer containing at least one of acrylic acid, methacrylate, maleate, acrylic ester, methacrylic acid ester, maleate ester, and styrene derivative monomer, or a polyamide-based polymer compound.
Claim 17
Dependent Claim
27 words
The biosensor according to claim 1 , wherein the electrodes are at least one selected from the group consisting of gold electrodes, carbon electrodes, and silver electrodes.
Claim 18
Dependent Claim
14 words
The biosensor according to claim 1 , wherein the reagent contains a redox enzyme.
Claim 19
Dependent Claim
24 words
The biosensor according to claim 1 , wherein the reagent contains a redox enzyme and an electron acceptor in a reaction of the enzyme.
Claim 20
Dependent Claim
15 words
The biosensor according to claim 1 , wherein a sample to be measured is blood.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2009-01-02 | 2009-07-04 | 2010-01-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2013-01-02 | 2013-07-04 | 2014-01-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2017-01-02 | 2017-07-04 | 2018-01-03 | $7700.00 | Window Closed / Lapsed |