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US6989243B2
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Method of determining the concentration of an analyte in a physiological sample
Assignee: Cilag GmbH International
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Filing: 2002-05-24
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Granted: 2006-01-24
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Expires: 2022-05-24
Abstract
Abstract Methods for determining the concentration of an analyte, e.g. glucose, in a physiological sample, are provided. The subject methods use reagent test strips which include one or more members of an analyte oxidation signal producing system and at least one hemolyzing agent. The subject methods are particularly suited for use in the detection of blood glucose concentrations.
Inventors
- 👤 Adva Yani
- 👤 Paing C. Huang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 00:40
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/26; C12Q1/28; C12Q1/54; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/521; Y; Y10; Y10S; Y10S435/00; Y10S435/975
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
111 words
A method of determining a analyte concentration in a physiological sample, said method comprising: (a) applying said physiological sample to a test strip comprising: (i) a porous matrix; (ii) at least one member of an analyte oxidation signal producing system; and (iii) at least one hemolyzing agent, wherein said hemolyzing agent is present in an amount sufficient to produce hemolysis which is equivalent to a hemolysate concentration in a physiological sample applied to said porous matrix in an amount ranging from about 5 to 20% by volume; (b) detecting a signal produced by said signal producing system; and (c) relating said detected signal to the analyte concentration in said physiological sample.
Claim 2
Independent Claim
111 words
A method of determining a analyte concentration in a physiological sample, said method comprising: (a) applying said physiological sample to a test strip comprising: (i) a porous matrix; (ii) at least one member of an analyte oxidation signal producing system; and (iii) at least one hemolyzing agent, wherein said hemolyzing agent is present in an amount sufficient to produce hemolysis which is equivalent to a hemolysate concentration in a physiological sample applied to said porous matrix in an amount ranging from about 5 to 20% by volume; (b) detecting a signal produced by said signal producing system; and (c) relating said detected signal to the analyte concentration in said physiological sample.
Claim 3
Dependent Claim
12 words
The method according to claim 1 , wherein said analyte is glucose.
Claim 4
Dependent Claim
14 words
The method according to claim 1 , wherein said physiological sample is whole blood.
Claim 5
Dependent Claim
47 words
The method according to claim 1 , wherein said hemolyzing agent is present in an amount sufficient to produce hemolysis which is equivalent to the hemolysate concentration in a physiological sample applied to said porous matrix in an amount ranging from about 5 to 20% by volume.
Claim 6
Dependent Claim
20 words
The method according to claim 1 , wherein said detecting and relating steps are carried out by an automated instrument.
References Cited (Backward Citations)
DE708335C
Cited
DE695936C
Cited
DE840124C
Cited
US4297238A
Cited
US4551427A
Cited
DE3424355A1
Cited
JPS62296987A
Cited
US5563042A
Cited
WO1990012889A1
Cited
WO1990012890A1
Cited
US5278047A
Cited
US5866349A
Cited
JPH03180762A
Cited
US5258047A
Cited
US5541117A
Cited
US5968836A
Cited
DE4229477A1
Cited
US5843691A
Cited
EP0638805A2
Cited
US5705357A
Cited
US5709837A
Cited
US6027692A
Cited
US5789255A
Cited
US5753452A
Cited
US5972294A
Cited
US5891731A
Cited
US6485923B1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2009-01-23 | 2009-07-25 | 2010-01-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2013-01-23 | 2013-07-25 | 2014-01-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2017-01-23 | 2017-07-25 | 2018-01-24 | $7700.00 | Window Closed / Lapsed |